⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10356515 | 0.67 | — | — | |
| SCHEMBL313893 | 0.65 | — | — | |
| SCHEMBL15576727 | 0.65 | — | — | |
| SCHEMBL15450866 | 0.63 | — | — | |
| SCHEMBL23759947 | 0.60 | — | — | |
| SCHEMBL19650474 | 0.60 | — | — | |
| SCHEMBL18531821 | 0.60 | — | — | |
| SCHEMBL21301176 | 0.60 | — | — | |
| SCHEMBL14950512 | 0.60 | — | — | |
| SCHEMBL2126835 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220236294-A1 | Methods for Evaluation and Treatment of Alzheimer's Disease and Applications Thereof | HUNTINGTON MEDICAL RESEARCH INSTITUTES (US) | 2022-07-28 | — | — | US | disclosed |
| US-11345725-B2 | Bis-thioether stapled peptides as inhibitors of PRC2 function | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) | 2022-05-31 | — | — | US | disclosed |
| EP-3672971-B1 | TRIAZOLO PYRIDINES AS MODULATORS OF GAMMA-SECRETASE | BOEHRINGER INGELHEIM INT (DE) | 2021-07-14 | — | — | EP | disclosed |
| US-20210079044-A1 | BIS-THIOETHER STAPLED PEPTIDES AS INHIBITORS OF PRC2 FUNCTION | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK | 2021-03-18 | — | — | US | disclosed |
| US-10919953-B2 | FcgammaRIIB-specific Fc region variant | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2021-02-16 | — | — | US | disclosed |