Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.58 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 4/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10287769 | 0.90 | HTR7 (0.71) | HTR7TAAR1MAOB | |
| SCHEMBL10279799 | 0.84 | HTR7 (0.82) | HTR7TAAR1MAOAFFAR1HTR6 | |
| SCHEMBL13958743 | 0.83 | TAAR1 (0.50) | HTR7TAAR1MAOAMAOBFFAR1 | |
| SCHEMBL15138999 | 0.82 | MAOA (0.50) | HTR7TAAR1MAOAMAOBHTR6 | |
| SCHEMBL13958745 | 0.81 | TAAR1 (0.61) | HTR7TAAR1MAOAFFAR1HTR6 | |
| SCHEMBL3191746 | 0.81 | HTR7 (0.63) | HTR7TAAR1MAOAFFAR1CYP2A6 | |
| SCHEMBL29706557 | 0.79 | MAOA (0.57) | HTR7TAAR1MAOAMAOBHTR6 | |
| SCHEMBL4035870 | 0.79 | MAOA (0.57) | HTR7TAAR1MAOAMAOBHTR6 | |
| SCHEMBL26313628 | 0.79 | TAAR1 (0.49) | HTR7TAAR1MAOAMAOBFFAR1 | |
| SCHEMBL3229152 | 0.78 | MAOA (0.55) | HTR7TAAR1MAOAMAOBHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012027230-A1 | FACIALLY AMPHIPHILIC COMPOUNDS, COMPOSITIONS, AND USES THEREOF IN TREATING CANCER | POLYMEDIX, INC. (US) | 2012-03-01 | — | — | WO | disclosed |
| WO-2012006315-A2 | METHODS OF IMMUNE MODULATION | POLYMEDIX, INC. (US) | 2012-01-12 | — | — | WO | disclosed |