SCHEMBL22986071

SCHEMBL22986071

C=CC(CCN(C)C)C(=O)OC

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.34
CHRM4 P08173 1/20 0.34
CHRM5 P08912 1/20 0.34
CHRM1 P11229 1/20 0.34
CHRNB2 P17787 1/20 0.34
CHRM3 P20309 1/20 0.34
CHRNA4 P43681 1/20 0.34
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
UTS2R Q9UKP6 3/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
ZDHHC7 Q9NXF8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20108098 0.82 CHRM2 (0.32) CHRM2CHRM4CHRM5CHRM1CHRNB2
SCHEMBL15111650 0.79 CA1 (0.42) CHRM1CHRNB2CHRM3CHRNA4MEN1
SCHEMBL19085523 0.79 TSHR (0.32) MEN1KMT2AUTS2R
SCHEMBL4954690 0.77 TSHR (0.39) MEN1KMT2ACA1CA2SMN1; SMN2
SCHEMBL15111700 0.76 CA2 (0.53) CA1CA2ZDHHC7
SCHEMBL23483674 0.75 CA1 (0.37) CHRM2CHRM4CHRM5CHRM1CHRNB2
SCHEMBL3274327 0.74 ZDHHC7 (0.53) CA1CA2ZDHHC7
SCHEMBL13955398 0.74 CYP2C9 (0.40) KMT2A
SCHEMBL13895351 0.74
SCHEMBL6272993 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4289951-A2 CIRCULAR RNA COMPOSITIONS AND METHODS Orna Therapeutics, Inc. (US) 2023-12-13 EP disclosed
WO-2021030701-A1 IMPROVED LIPID NANOPARTICLES FOR DELIVERY OF NUCLEIC ACIDS Acuitas Therapeutics, Inc. (CA) 2021-02-18 WO disclosed