Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22986071 | 0.82 | CHRM2 (0.34) | CHRM2CHRM4CHRM5CHRM1CHRNB2 | |
| SCHEMBL25126296 | 0.76 | CA1 (0.34) | CHRM2CHRM4CHRM5CHRM1CHRNB2 | |
| SCHEMBL13307459 | 0.70 | CHRNB2 (0.39) | CHRM2CHRM4CHRM5CHRM1CHRNB2 | |
| SCHEMBL23483674 | 0.69 | CA1 (0.37) | CHRM2CHRM4CHRM5CHRM1CHRNB2 | |
| SCHEMBL2446304 | 0.68 | LTA4H (0.41) | CHRM2CHRM4CHRM5CHRM1CHRNB2 | |
| SCHEMBL4603026 | 0.68 | LTA4H (0.41) | CHRM2CHRM4CHRM5CHRM1CHRNB2 | |
| SCHEMBL11610977 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL2445581 | 0.67 | LTA4H (0.40) | CHRM2CHRM4CHRM5CHRM1CHRNB2 | |
| SCHEMBL25657480 | 0.67 | CHRNB2 (0.36) | CHRM2CHRM4CHRM5CHRM1CHRNB2 | |
| SCHEMBL14327274 | 0.67 | CHRNB2 (0.36) | CHRM2CHRM4CHRM5CHRM1CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023250375-A1 | CIRCULAR RNA ENCODING CHIMERIC ANTIGEN RECEPTORS TARGETING BCMA | ORNA THERAPEUTICS, INC. (US) | 2023-12-28 | — | — | WO | disclosed |
| WO-2022261490-A2 | CIRCULAR RNA COMPOSITIONS AND METHODS | ORNA THERAPEUTICS, INC. (US) | 2022-12-15 | — | — | WO | disclosed |
| WO-2018081480-A1 | LIPID NANOPARTICLE FORMULATIONS | Acuitas Therapeutics, Inc. (CA) | 2018-05-03 | — | — | WO | disclosed |