Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 4/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 4/20 | 0.34 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | TRPC3 | Q13507 | 2/20 | 0.33 |
| ▸ | TRPC7 | Q9HCX4 | 2/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | GPR39 | O43194 | 1/20 | 0.32 |
| ▸ | TNKS | O95271 | 1/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.32 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.32 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 2/20 | 0.32 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.31 |
| ▸ | CCNK | O75909 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.31 |
| ▸ | F13A1 | P00488 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22987467 | 0.91 | NR1H2 (0.35) | NR1H2NR1H3BRD4CREBBPPARP1 | |
| SCHEMBL22988133 | 0.91 | ADORA3 (0.34) | PARP1TRPC3TRPC7USP30GPR39 | |
| SCHEMBL22988150 | 0.90 | USP30 (0.35) | BRD4CREBBPPARP1TRPC3TRPC7 | |
| SCHEMBL22987609 | 0.90 | TRPC3 (0.39) | NR1H2NR1H3TRPC3TRPC7USP30 | |
| SCHEMBL22987625 | 0.89 | BCL9 (0.37) | NR1H2NR1H3PARP1TRPC3TRPC7 | |
| SCHEMBL22987607 | 0.89 | TRPC3 (0.36) | NR1H2NR1H3PARP1TRPC3TRPC7 | |
| SCHEMBL29450017 | 0.87 | USP30 (0.34) | PARP1USP30GPR39TNKSTNKS2 | |
| SCHEMBL22987658 | 0.86 | NR1H2 (0.37) | NR1H2NR1H3PARP1TRPC3TRPC7 | |
| SCHEMBL25118878 | 0.86 | NR1H2 (0.37) | NR1H2NR1H3PARP1TRPC3TRPC7 | |
| SCHEMBL22987752 | 0.85 | NR1H2 (0.34) | NR1H2NR1H3PARP1TRPC3TRPC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230113037-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | BAYER AKTIENGESELLSCHAFT (DE) | 2023-04-13 | — | — | US | disclosed |
| WO-2021028382-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | BAYER AKTIENGESELLSCHAFT (DE) | 2021-02-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230113037-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | AHR, HRH4, HRH1 | NR1H2 296/4885NR1H3 422/4885BRD4 443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.