Imidazole

Imidazole

SCHEMBL2298774

O[Si](O)(O)O.c1c[nH]cn1.c1c[nH]cn1.c1c[nH]cn1.c1c[nH]cn1

nearest known ligand 0.81

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.81
FKBP5 Q13451 1/20 0.81

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Imidazole SCHEMBL31619983 1.00 ALDH1A1 (0.81) ALDH1A1FKBP5
Imidazole SCHEMBL27877106 1.00 ALDH1A1 (0.81) ALDH1A1FKBP5
Imidazole SCHEMBL4200475 0.94 ALDH1A1 (0.93) ALDH1A1FKBP5
Imidazole SCHEMBL1585849 0.94
Imidazole SCHEMBL5838654 0.90
Imidazole SCHEMBL5838661 0.90 ALDH1A1 (0.87) ALDH1A1FKBP5
Imidazole SCHEMBL1331920 0.90
Imidazole SCHEMBL897 0.90
Imidazole SCHEMBL2684565 0.90 ALDH1A1 (1.00) ALDH1A1FKBP5
Imidazole SCHEMBL1331382 0.90

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2536381-A1 EFFECTIVE DEPILATORY ARTICLE The Procter & Gamble Company (US) 2012-12-26 EP claimed
EP-2356968-B1 Substrate-based depilatory article PROCTER & GAMBLE (US) 2012-06-20 EP claimed
WO-2011103220-A1 SUBSTRATE-BASED DEPILATORY ARTICLE THE PROCTER & GAMBLE COMPANY (US) 2011-08-25 WO claimed
WO-2011103233-A1 EFFECTIVE DEPILATORY ARTICLE THE PROCTER & GAMBLE COMPANY (US) 2011-08-25 WO claimed
US-20110197375-A1 Effective Depilatory Article THE PROCTER & GAMBLE COMPANY 2011-08-18 US claimed
US-20110198263-A1 Substrate-Based Depilatory Article THE PROCTER & GAMBLE COMPANY 2011-08-18 US claimed
EP-2356968-A1 Substrate-based depilatory article The Procter & Gamble Company (US) 2011-08-17 EP claimed
EP-2767311-B1 Stable personal care article PROCTER & GAMBLE (US) 2018-01-10 EP disclosed
US-9248085-B2 Effective depilatory article THE PROCTER & GAMBLE COMPANY (US) 2016-02-02 US disclosed
US-20150224040-A1 Stable Personal Care Article THE PROCTER & GAMBLE COMPANY (US) 2015-08-13 US disclosed
EP-2559420-B1 Effective depilatory article PROCTER & GAMBLE (US) 2014-10-15 EP disclosed
WO-2014126738-A2 STABLE PERSONAL CARE ARTICLE THE PROCTER & GAMBLE COMPANY (US) 2014-08-21 WO disclosed
EP-2767311-A1 Stable personal care article The Procter & Gamble Company (US) 2014-08-20 EP disclosed
EP-2356918-A1 Facial depilatory article The Procter & Gamble Company (US) 2011-08-17 EP disclosed
EP-2356968-A1 Substrate-based depilatory article The Procter & Gamble Company (US) 2011-08-17 EP disclosed
EP-2356964-A1 Tensionable depilatory article The Procter & Gamble Company (US) 2011-08-17 EP disclosed
EP-2356967-A1 Durable depilatory article The Procter & Gamble Company (US) 2011-08-17 EP disclosed
EP-2356965-A1 Method of depilation The Procter & Gamble Company (US) 2011-08-17 EP disclosed
EP-2356963-A1 Adherent depilatory article The Procter & Gamble Company (US) 2011-08-17 EP disclosed
EP-2356966-A1 Conformable depilatory article The Procter & Gamble Company (US) 2011-08-17 EP disclosed