Imidazole

Imidazole

SCHEMBL4200475

[C].c1c[nH]cn1.c1c[nH]cn1

nearest known ligand 0.93

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.93
FKBP5 Q13451 1/20 0.93

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Imidazole SCHEMBL1585849 1.00
Imidazole SCHEMBL28744226 0.96 ALDH1A1 (1.00) ALDH1A1FKBP5
Imidazole SCHEMBL1331382 0.96
Imidazole SCHEMBL19028065 0.96 ALDH1A1 (1.00) ALDH1A1FKBP5
Imidazole SCHEMBL897 0.96
Imidazole SCHEMBL30382963 0.96
Imidazole SCHEMBL2684565 0.96 ALDH1A1 (1.00) ALDH1A1FKBP5
Imidazole SCHEMBL1331920 0.96
Imidazole SCHEMBL2635292 0.96
Imidazole SCHEMBL2298774 0.94 ALDH1A1 (0.81) ALDH1A1FKBP5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12566113-B2 Reversible fixing reagents and methods of use thereof 10X GENOMICS, INC. (US) 2026-03-03 US disclosed
CN-119432211-A Quaternized bisimidazolyl carbon nanotube modified polyurethane coating and preparation method thereof 湖北省北巷南茂科技有限公司 2025-02-14 CN disclosed
US-20220334031-A1 REVERSIBLE FIXING REAGENTS AND METHODS OF USE THEREOF 10X GENOMICS, INC. (US) 2022-10-20 US disclosed
CN-108513574-A N-sulfonylated pyrazolo [3,4-b ] pyridine-6-carboxamides and methods of use 艾伯维公司 2018-09-07 CN disclosed
CN-107848962-A UREA DERIVATIVE OR PHARMACOLOGICALLY ACCEPTABLE SALT THEREOF 杏林制药株式会社 2018-03-27 CN disclosed
US-20160313356-A1 METHODS AND KITS FOR DETECTING FUNGAL INFECTION SEMOREX INC. (US) 2016-10-27 US disclosed
CN-103534258-B Tyrosine kinase inhibitor 普林斯匹亚生物制药公司 2016-09-14 CN disclosed
US-9383373-B2 Methods for detecting fungal infection SEMOREX INC. (US) 2016-07-05 US disclosed
EP-1955069-B1 METHODS AND KITS FOR DETECTING FUNGAL INFECTION SEMOREX INC (US) 2015-03-18 EP disclosed
US-20090111129-A1 Methods and Kits for Detecting Fungal Infection SEMOREX INC. (US) 2009-04-30 US disclosed
EP-1955069-A2 METHODS AND KITS FOR DETECTING FUNGAL INFECTION Semorex Inc. (US) 2008-08-13 EP disclosed
WO-2007057891-A2 METHODS AND KITS FOR DETECTING FUNGAL INFECTION SEMOREX INC. (US) 2007-05-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12566113-B2 Reversible fixing reagents and methods of use thereof SMCHD1, H1-10, FLT3 ALDH1A1 117/4885FKBP5 1872/4885
US-20220334031-A1 REVERSIBLE FIXING REAGENTS AND METHODS OF USE THEREOF PTMS, FGB, CPSF1 ALDH1A1 4091/4885FKBP5 1122/4885
US-20090111129-A1 Methods and Kits for Detecting Fungal Infection ERG28, CYP51A1, HSD17B11 ALDH1A1 831/4885FKBP5 687/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.