Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 14/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 11/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 10/20 | 0.48 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.40 |
| ▸ | CSF1R | P07333 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22979975 | 0.88 | HSP90AB1 (0.42) | ADORA2AADORA3ADORA1HSP90AB1CSF1R | |
| SCHEMBL22988169 | 0.86 | ADORA3 (0.48) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL22988399 | 0.84 | ADORA2A (0.45) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL22988458 | 0.82 | ADORA2A (0.43) | ADORA2AADORA3ADORA1 | |
| SCHEMBL22987424 | 0.78 | ADORA3 (0.40) | ADORA2AADORA3ADORA1HSP90AB1 | |
| SCHEMBL22979176 | 0.77 | ADORA3 (0.39) | ADORA2AADORA3ADORA1 | |
| SCHEMBL22987463 | 0.77 | ADORA3 (0.39) | ADORA2AADORA3ADORA1 | |
| SCHEMBL22987894 | 0.76 | HSP90AB1 (0.45) | ADORA2AADORA3ADORA1HSP90AB1ADORA2B | |
| SCHEMBL22978982 | 0.76 | ADORA3 (0.38) | ADORA2AADORA3ADORA1 | |
| SCHEMBL22987969 | 0.76 | GABRP (0.48) | ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021028382-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | BAYER AKTIENGESELLSCHAFT (DE) | 2021-02-18 | — | — | WO | disclosed |