Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22987825 | 0.80 | CSNK1D (0.59) | ADORA3ADORA1ADORA2ARXFP1TP53 | |
| SCHEMBL22987873 | 0.79 | ADORA3 (0.50) | ADORA3ADORA1ADORA2ARXFP1TP53 | |
| SCHEMBL22988327 | 0.74 | ADORA1 (0.47) | ADORA3ADORA1ADORA2ARXFP1TP53 | |
| SCHEMBL743593 | 0.73 | RXFP1 (0.58) | ADORA3ADORA1ADORA2ARXFP1TP53 | |
| SCHEMBL22988309 | 0.72 | ADORA3 (0.53) | ADORA3ADORA1ADORA2ATP53MAPT | |
| SCHEMBL22988304 | 0.72 | ADORA3 (0.65) | ADORA3ADORA1ADORA2ATHRBMAPT | |
| SCHEMBL22988235 | 0.71 | ADORA3 (0.51) | ADORA3ADORA1ADORA2ATP53MAPT | |
| SCHEMBL22988361 | 0.70 | PDE10A (0.53) | ADORA3ADORA1ADORA2ARXFP1THRB | |
| SCHEMBL18948427 | 0.69 | PDE10A (0.63) | ADORA3ADORA1TP53PDPK1 | |
| SCHEMBL24209870 | 0.68 | ADORA3 (0.71) | ADORA3ADORA1ADORA2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021028382-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | BAYER AKTIENGESELLSCHAFT (DE) | 2021-02-18 | — | — | WO | disclosed |