Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22988309 | 0.86 | ADORA3 (0.53) | ADORA3ADORA1ADORA2ATP53MAPT | |
| SCHEMBL22988115 | 0.86 | ADORA3 (0.50) | ADORA3ADORA1RXFP1TP53THRB | |
| SCHEMBL22987825 | 0.81 | CSNK1D (0.59) | ADORA3ADORA1ADORA2ARXFP1TP53 | |
| SCHEMBL22988124 | 0.79 | ADORA3 (0.48) | ADORA3ADORA1ADORA2ARXFP1TP53 | |
| SCHEMBL30393378 | 0.77 | NPC1 (0.52) | ADORA3ADORA1RXFP1TP53MAPT | |
| SCHEMBL29649000 | 0.76 | TP53 (0.46) | ADORA3ADORA1RXFP1TP53THRB | |
| SCHEMBL22988327 | 0.76 | ADORA1 (0.47) | ADORA3ADORA1ADORA2ARXFP1TP53 | |
| SCHEMBL29645973 | 0.76 | TP53 (0.46) | ADORA3ADORA1RXFP1TP53THRB | |
| SCHEMBL22988160 | 0.75 | GABRP (0.71) | RXFP1TP53POLB | |
| SCHEMBL743593 | 0.75 | RXFP1 (0.58) | ADORA3ADORA1ADORA2ARXFP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021028382-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | BAYER AKTIENGESELLSCHAFT (DE) | 2021-02-18 | — | — | WO | disclosed |