SCHEMBL22988511

SCHEMBL22988511

c1ccc(-n2c3ccc4cccc5c4c3c3c4c(ccc32)[nH]c2cccc-5c24)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK4 P11802 4/20 0.40
CCND1 P24385 4/20 0.40
MAPK1 P28482 3/20 0.35
ATM Q13315 3/20 0.35
L3MBTL1 Q9Y468 3/20 0.35
ALDH1A1 P00352 3/20 0.35
TSHR P16473 2/20 0.35
HSD17B10 Q99714 2/20 0.35
PARP1 P09874 2/20 0.34
LMNA P02545 2/20 0.34
PDE10A Q9Y233 2/20 0.34
KDM4E B2RXH2 2/20 0.33
TP53 P04637 1/20 0.33
HPGD P15428 1/20 0.33
CASP1 P29466 1/20 0.33
CASP7 P55210 1/20 0.33
HIF1A Q16665 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
PDE7A Q13946 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23024755 0.93 CDK4 (0.39) CDK4CCND1MAPK1ATML3MBTL1
SCHEMBL15835261 0.86 L3MBTL1 (0.39) CDK4CCND1MAPK1ATML3MBTL1
SCHEMBL23024779 0.85 CDK4 (0.41) CDK4CCND1ALDH1A1HPGDCCNB2
SCHEMBL24245675 0.85 ALDH1A1 (0.45) MAPK1ATML3MBTL1ALDH1A1TSHR
SCHEMBL22257287 0.82 ALDH1A1 (0.47) MAPK1ATML3MBTL1ALDH1A1TSHR
SCHEMBL24245768 0.82 ATM (0.42) MAPK1ATML3MBTL1ALDH1A1TSHR
SCHEMBL21630342 0.81 ALDH1A1 (0.54) CDK4CCND1MAPK1ATML3MBTL1
SCHEMBL24117123 0.81 CDK4 (0.34) CDK4CCND1MAPK1ATML3MBTL1
SCHEMBL27317106 0.79 KDM4E (0.39) CDK4CCND1ATML3MBTL1PARP1
SCHEMBL21366739 0.78 ALDH1A1 (0.52) MAPK1ATML3MBTL1ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021029715-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2021-02-18 WO disclosed