SCHEMBL22988930

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL23030549	0.85	MAPK1 (0.38)	ALDH1A1HSD17B10TSHRCYP1A2HPGD
	SCHEMBL30352822	0.83	ALDH1A1 (0.59)	ALDH1A1HSD17B10TSHRCYP1A2HPGD
	SCHEMBL6254645	0.83	ALDH1A1 (0.59)	ALDH1A1HSD17B10TSHRCYP1A2HPGD
	SCHEMBL22988505	0.81	MAPK1 (0.42)	ALDH1A1HSD17B10TSHRCYP1A2HPGD
	SCHEMBL24266188	0.80	CDK4 (0.38)	ALDH1A1HSD17B10TSHRCDK4CCND1
	SCHEMBL31568010	0.77	ALDH1A1 (0.61)	ALDH1A1HSD17B10TSHRCYP1A2HPGD
	SCHEMBL1273519	0.77	ALDH1A1 (0.61)	ALDH1A1HSD17B10TSHRCYP1A2HPGD
	SCHEMBL14951814	0.76	L3MBTL1 (0.50)	ALDH1A1HSD17B10TSHRCYP1A2HPGD
	SCHEMBL3727430	0.76	ALDH1A1 (0.56)	ALDH1A1HSD17B10TSHRCYP1A2HPGD
	SCHEMBL29671006	0.76	ALDH1A1 (0.56)	ALDH1A1HSD17B10TSHRCYP1A2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.