SCHEMBL22989080

SCHEMBL22989080

c1ccc(-c2nc(-c3ccc4c(c3)c3ccccc3n4-c3ccccc3)nc(-n3c4ccc5cccc6oc7cccc8ccc3c(c87)c4c56)n2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.38
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
PTGER4 P35408 1/20 0.35
ABCG2 Q9UNQ0 3/20 0.32
SIRT2 Q8IXJ6 1/20 0.32
SIRT1 Q96EB6 1/20 0.32
PTGES O14684 1/20 0.32
RXFP1 Q9HBX9 1/20 0.31
KMT2A Q03164 3/20 0.31
LMNA P02545 2/20 0.31
MEN1 O00255 2/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
ALDH1A1 P00352 1/20 0.31
POLB P06746 1/20 0.31
TSHR P16473 1/20 0.31
BRCA1 P38398 1/20 0.31
HSD17B10 Q99714 1/20 0.31
NPY5R Q15761 1/20 0.31
NPC1 O15118 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22989221 0.90 KDM4E (0.37) KDM4EATML3MBTL1PTGER4SIRT2
SCHEMBL24151762 0.88 L3MBTL1 (0.43) KDM4EATML3MBTL1PTGER4ABCG2
SCHEMBL24154007 0.87 L3MBTL1 (0.42) KDM4EATML3MBTL1PTGER4ABCG2
SCHEMBL22893773 0.86 KDM4E (0.38) KDM4EATML3MBTL1PTGER4ABCG2
SCHEMBL21965527 0.86 L3MBTL1 (0.51) KDM4EATML3MBTL1PTGER4ABCG2
SCHEMBL21965209 0.86 L3MBTL1 (0.51) KDM4EATML3MBTL1PTGER4ABCG2
SCHEMBL21903333 0.86 L3MBTL1 (0.51) KDM4EATML3MBTL1PTGER4ABCG2
SCHEMBL14733847 0.86 KDM4E (0.41) KDM4EATML3MBTL1PTGER4SIRT2
SCHEMBL17246664 0.85 L3MBTL1 (0.43) KDM4EATML3MBTL1PTGER4ABCG2
SCHEMBL19239359 0.85 KDM4E (0.37) KDM4EATML3MBTL1PTGER4ABCG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021029757-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME 주식회사 엘지화학 2021-02-18 WO disclosed