SCHEMBL22989112

SCHEMBL22989112

c1ccc(-c2cccc(-c3nc4ccccc4nc3-n3c4ccc5cccc6oc7cccc8ccc3c(c87)c4c56)c2)cc1

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CASP1 P29466 1/20 0.38
HSD17B10 Q99714 1/20 0.38
PDE10A Q9Y233 5/20 0.36
L3MBTL1 Q9Y468 3/20 0.36
HRH4 Q9H3N8 1/20 0.35
PIK3R1 P27986 1/20 0.33
PIK3CA P42336 1/20 0.33
GAA P10253 2/20 0.32
KDM4E B2RXH2 3/20 0.32
ALDH1A1 P00352 3/20 0.32
MEN1 O00255 1/20 0.32
LMNA P02545 1/20 0.32
KMT2A Q03164 1/20 0.32
ATM Q13315 1/20 0.32
HTT P42858 1/20 0.32
HPGD P15428 1/20 0.32
RAD51 Q06609 1/20 0.31
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24245523 0.94 CASP1 (0.39) CASP1HSD17B10PDE10AL3MBTL1HRH4
SCHEMBL22989108 0.93 CASP1 (0.42) CASP1HSD17B10PDE10AL3MBTL1HRH4
SCHEMBL22989116 0.93 CASP1 (0.44) CASP1HSD17B10PDE10AL3MBTL1HRH4
SCHEMBL23030689 0.92 CASP1 (0.34) CASP1HSD17B10PDE10AL3MBTL1HRH4
SCHEMBL22988548 0.90 CASP1 (0.34) CASP1HSD17B10PDE10AL3MBTL1HRH4
SCHEMBL22989111 0.89 PDE10A (0.36) CASP1HSD17B10PDE10AL3MBTL1PIK3CA
SCHEMBL23030569 0.88 SMN1; SMN2 (0.35) CASP1HSD17B10PDE10AL3MBTL1PIK3R1
SCHEMBL24245683 0.87 PDE10A (0.37) CASP1HSD17B10PDE10AL3MBTL1HRH4
SCHEMBL23874837 0.86 HSD17B10 (0.35) CASP1HSD17B10PDE10AL3MBTL1HRH4
SCHEMBL22989115 0.85 AHR (0.33) CASP1HSD17B10PDE10AL3MBTL1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021029757-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME 주식회사 엘지화학 2021-02-18 WO disclosed