SCHEMBL22989111

SCHEMBL22989111

c1ccc2cc(-c3nc4ccccc4nc3-n3c4ccc5cccc6oc7cccc8ccc3c(c87)c4c56)ccc2c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 3/20 0.36
L3MBTL1 Q9Y468 2/20 0.34
HSD17B10 Q99714 2/20 0.33
CASP1 P29466 1/20 0.33
NQO2 P16083 1/20 0.33
DHODH Q02127 1/20 0.32
SRC P12931 2/20 0.32
ALDH1A1 P00352 2/20 0.32
NPC1 O15118 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C9 P11712 1/20 0.32
HPGD P15428 1/20 0.32
TSHR P16473 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
MAPK8 P45983 1/20 0.32
MAPK9 P45984 1/20 0.32
MAPK10 P53779 1/20 0.32
UTRN P46939 1/20 0.32
PIK3CD O00329 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23030691 0.92 PDE10A (0.33) PDE10AL3MBTL1HSD17B10CASP1SRC
SCHEMBL22989112 0.89 CASP1 (0.38) PDE10AL3MBTL1HSD17B10CASP1ALDH1A1
SCHEMBL22989108 0.89 CASP1 (0.42) PDE10AL3MBTL1HSD17B10CASP1DHODH
SCHEMBL22989116 0.89 CASP1 (0.44) PDE10AL3MBTL1HSD17B10CASP1ALDH1A1
SCHEMBL22989115 0.89 AHR (0.33) PDE10AL3MBTL1HSD17B10CASP1ALDH1A1
SCHEMBL22989218 0.87 L3MBTL1 (0.36) PDE10AL3MBTL1DHODHALDH1A1HPGD
SCHEMBL23030487 0.84 ALDH1A1 (0.37) PDE10AL3MBTL1HSD17B10CASP1ALDH1A1
SCHEMBL21423222 0.84 PDE10A (0.35) PDE10AL3MBTL1HSD17B10CASP1NQO2
SCHEMBL22989263 0.84 PDE10A (0.35) PDE10AL3MBTL1NQO2DHODHSRC
SCHEMBL22989118 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021029757-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME 주식회사 엘지화학 2021-02-18 WO disclosed