SCHEMBL22989246

SCHEMBL22989246

c1ccc(-c2cccc(-c3nc(-c4ccccc4)nc(-c4ccc5cc(-n6c7ccc8cccc9sc%10cccc%11ccc6c(c%11%10)c7c89)ccc5c4)n3)c2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 2/20 0.36
CYP11B2 P19099 2/20 0.36
MAPK10 P53779 2/20 0.34
MAPK9 P45984 1/20 0.34
NR3C1 P04150 1/20 0.34
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TP53 P04637 1/20 0.33
CYP1A2 P05177 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HSD17B10 Q99714 1/20 0.33
CYP17A1 P05093 1/20 0.32
CYP19A1 P11511 1/20 0.32
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31
HSD17B1 P14061 1/20 0.31
HSD17B2 P37059 1/20 0.31
PDE6D O43924 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22989247 0.97 MAPK10 (0.36) CYP11B1CYP11B2MAPK10MAPK9NR3C1
SCHEMBL22989250 0.95 MAPK10 (0.38) CYP11B1CYP11B2MAPK10MAPK9KDM4E
SCHEMBL22988979 0.93 MAPK10 (0.35) CYP11B1CYP11B2MAPK10MAPK9NR3C1
SCHEMBL22989255 0.91 RPA1 (0.33) MAPK10MAPK9KDM4EMEN1ALDH1A1
SCHEMBL22988983 0.88 PDE1B (0.34) KDM4EMEN1ALDH1A1KMT2ASMN1; SMN2
SCHEMBL22989228 0.88 S1PR5 (0.32) MAPK10MAPK9
SCHEMBL22988912 0.86 KDM4E (0.36) CYP11B1CYP11B2MAPK10MAPK9NR3C1
SCHEMBL22989256 0.86 SMN1; SMN2 (0.38) CYP11B1CYP11B2MAPK10MAPK9KDM4E
SCHEMBL22989182 0.86 MEN1 (0.40) KDM4EMEN1TP53CYP1A2KMT2A
SCHEMBL22989253 0.85 KDM4E (0.31) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021029757-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME 주식회사 엘지화학 2021-02-18 WO disclosed