SCHEMBL22989247

SCHEMBL22989247

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc4cc(-n5c6ccc7cccc8sc9cccc%10ccc5c(c%109)c6c78)ccc4c3)n2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK10 P53779 7/20 0.36
MAPK9 P45984 6/20 0.36
KMT2A Q03164 4/20 0.35
SMN1; SMN2 Q16637 4/20 0.35
MEN1 O00255 3/20 0.35
ALDH1A1 P00352 3/20 0.35
KDM4E B2RXH2 2/20 0.35
TP53 P04637 2/20 0.35
CYP1A2 P05177 1/20 0.35
HSD17B10 Q99714 1/20 0.35
MAPT P10636 5/20 0.32
HPGD P15428 2/20 0.32
MAPK8 P45983 1/20 0.32
LMNA P02545 2/20 0.32
RPA1 P27694 1/20 0.32
GLA P06280 1/20 0.32
CYP17A1 P05093 1/20 0.31
CYP19A1 P11511 1/20 0.31
CYP11B1 P15538 1/20 0.31
CYP11B2 P19099 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22989250 0.99 MAPK10 (0.38) MAPK10MAPK9KMT2ASMN1; SMN2MEN1
SCHEMBL22989246 0.97 CYP11B1 (0.36) MAPK10MAPK9KMT2ASMN1; SMN2MEN1
SCHEMBL22988979 0.96 MAPK10 (0.35) MAPK10MAPK9KMT2ASMN1; SMN2MEN1
SCHEMBL22989255 0.92 RPA1 (0.33) MAPK10MAPK9KMT2ASMN1; SMN2MEN1
SCHEMBL22988983 0.91 PDE1B (0.34) KMT2ASMN1; SMN2MEN1ALDH1A1KDM4E
SCHEMBL22989228 0.91 S1PR5 (0.32) MAPK10MAPK9HPGD
SCHEMBL22989256 0.89 SMN1; SMN2 (0.38) MAPK10MAPK9KMT2ASMN1; SMN2MEN1
SCHEMBL22989253 0.88 KDM4E (0.31) KDM4EATM
SCHEMBL22989251 0.87 S1PR5 (0.31)
SCHEMBL22989184 0.87 MEN1 (0.41) KMT2ASMN1; SMN2MEN1KDM4ETP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021029757-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME 주식회사 엘지화학 2021-02-18 WO disclosed