SCHEMBL22989256

SCHEMBL22989256

c1ccc(-c2nc(-c3ccc4ccccc4c3)nc(-n3c4ccc5cccc6sc7cccc8ccc3c(c87)c4c56)n2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.38
MEN1 O00255 3/20 0.38
ALDH1A1 P00352 3/20 0.38
KMT2A Q03164 3/20 0.38
KDM4E B2RXH2 2/20 0.38
CYP1A2 P05177 2/20 0.38
TP53 P04637 2/20 0.38
HSD17B10 Q99714 1/20 0.38
CYP17A1 P05093 1/20 0.35
CYP19A1 P11511 1/20 0.35
CYP11B1 P15538 1/20 0.35
CYP11B2 P19099 1/20 0.35
HSD17B1 P14061 1/20 0.33
HSD17B2 P37059 1/20 0.33
CYP1A1 P04798 1/20 0.33
CYP1B1 Q16678 1/20 0.33
MAPT P10636 4/20 0.33
HPGD P15428 2/20 0.33
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22989250 0.91 MAPK10 (0.38) SMN1; SMN2MEN1ALDH1A1KMT2AKDM4E
SCHEMBL22989247 0.89 MAPK10 (0.36) SMN1; SMN2MEN1ALDH1A1KMT2AKDM4E
SCHEMBL22988979 0.88 MAPK10 (0.35) SMN1; SMN2MEN1ALDH1A1KMT2AKDM4E
SCHEMBL20276459 0.88 HSD17B1 (0.30) HSD17B1HSD17B2
SCHEMBL22989246 0.86 CYP11B1 (0.36) SMN1; SMN2MEN1ALDH1A1KMT2AKDM4E
SCHEMBL22988983 0.85 PDE1B (0.34) SMN1; SMN2MEN1ALDH1A1KMT2AKDM4E
SCHEMBL24406440 0.83 ALDH1A1 (0.38) SMN1; SMN2MEN1ALDH1A1KMT2AKDM4E
SCHEMBL22989255 0.82 RPA1 (0.33) SMN1; SMN2MEN1ALDH1A1KMT2AKDM4E
SCHEMBL22988932 0.81 ALDH1A1 (0.38) ALDH1A1KDM4EMAPTHPGDLMNA
SCHEMBL24741359 0.81 ALDH1A1 (0.40) SMN1; SMN2MEN1ALDH1A1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021029757-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME 주식회사 엘지화학 2021-02-18 WO disclosed