Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 3/20 | 0.33 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.31 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26311181 | 0.84 | ALOX5 (0.40) | ALOX5HDAC8PRKDCPTGES2GGPS1 | |
| SCHEMBL19774355 | 0.78 | ALOX5 (0.50) | ALOX5HDAC8PRKDCGGPS1ATM | |
| SCHEMBL26311421 | 0.77 | ALOX5 (0.41) | ALOX5HDAC8PRKDCPTGES2GGPS1 | |
| SCHEMBL26313244 | 0.77 | ALOX5 (0.38) | ALOX5HDAC8PRKDCPTGES2GGPS1 | |
| SCHEMBL22989927 | 0.77 | ALOX5 (0.45) | ALOX5HDAC8PRKDCPTGES2GGPS1 | |
| SCHEMBL12070586 | 0.75 | ALOX5 (0.41) | ALOX5HDAC8PRKDCPTGES2GGPS1 | |
| SCHEMBL20363748 | 0.75 | ALOX5 (0.50) | ALOX5HDAC8PRKDCGGPS1ATM | |
| SCHEMBL29313372 | 0.71 | ALOX5 (0.38) | ALOX5HDAC8PRKDCPTGES2GGPS1 | |
| SCHEMBL25744404 | 0.71 | ALOX5 (0.43) | ALOX5HDAC8PRKDCPTGES2GGPS1 | |
| SCHEMBL25165112 | 0.70 | ALOX5 (0.41) | ALOX5HDAC8ESR1ESR2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3481796-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2021-02-17 | — | — | EP | disclosed |