Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | PRKDC | P78527 | 5/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | AHR | P35869 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12070585 | 0.88 | ALOX5 (0.36) | ALOX5L3MBTL1HDAC8PGRPRKDC | |
| SCHEMBL20363748 | 0.81 | ALOX5 (0.50) | ALOX5HDAC8PGRPRKDCPIK3CD | |
| SCHEMBL23046780 | 0.80 | ALOX5 (0.51) | ALOX5L3MBTL1HDAC8PGRPRKDC | |
| SCHEMBL9890833 | 0.80 | ALOX5 (0.57) | ALOX5PGRPRKDCPIK3CDPIK3CB | |
| SCHEMBL19774355 | 0.78 | ALOX5 (0.50) | ALOX5HDAC8PGRPRKDCPIK3CD | |
| SCHEMBL21450759 | 0.78 | ALOX5 (0.56) | ALOX5PGRPRKDCPIK3CDPIK3CB | |
| SCHEMBL19546812 | 0.76 | L3MBTL1 (0.58) | L3MBTL1MEN1KMT2ACYP2C19MAOA | |
| SCHEMBL9890861 | 0.76 | ALOX5 (0.51) | ALOX5HDAC8PGRPRKDCPIK3CD | |
| SCHEMBL22989908 | 0.75 | ALOX5 (0.38) | ALOX5HDAC8PGRPRKDCGGPS1 | |
| SCHEMBL22854844 | 0.75 | ALOX5 (0.57) | ALOX5HDAC8PGRPRKDCPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011157790-A1 | ORGANIC ELECTRONIC DEVICES COMPRISING A LAYER OF A DIBENZOFURANE COMPOUND AND A 8-HYDROXYQUINOLINOLATO EARTH ALKALINE METAL, OR ALKALI METAL COMPLEX | BASF SE (DE) | 2011-12-22 | — | — | WO | disclosed |