Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7615076 | 0.65 | SMN1; SMN2 (0.37) | — | |
| SCHEMBL14616110 | 0.64 | — | — | |
| SCHEMBL601185 | 0.64 | — | — | |
| SCHEMBL31344350 | 0.61 | — | — | |
| SCHEMBL9815660 | 0.58 | — | — | |
| SCHEMBL2896873 | 0.58 | — | — | |
| SCHEMBL744461 | 0.57 | — | — | |
| SCHEMBL10546641 | 0.57 | — | — | |
| SCHEMBL13625216 | 0.57 | — | — | |
| Trimethylammonium SCHEMBL27845366 | 0.57 | GAA (0.38) | GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3778575-A1 | MODULATORS OF THE INTEGRATED STRESS PATHWAY | Calico Life Sciences LLC (US) | 2021-02-17 | — | — | EP | disclosed |