⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26088608 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL28115986 | 0.97 | — | — | |
| SCHEMBL5868448 | 0.80 | LMNA (0.39) | — | |
| SCHEMBL27981525 | 0.80 | CYP3A4 (0.39) | — | |
| SCHEMBL18029933 | 0.78 | — | — | |
| SCHEMBL17971806 | 0.78 | — | — | |
| SCHEMBL1660636 | 0.78 | — | — | |
| SCHEMBL7739770 | 0.78 | TRPA1 (0.32) | — | |
| SCHEMBL8984298 | 0.76 | — | — | |
| SCHEMBL12166986 | 0.76 | IDO1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3394068-A1 | TDO2 INHIBITORS | Genentech, Inc. (US) | 2018-10-31 | — | — | EP | claimed |
| WO-2017107979-A1 | TDO2 INHIBITORS | GENENTECH, INC. (US) | 2017-06-29 | — | — | WO | claimed |
| US-12391802-B2 | Method of forming semicrystalline polyetherimide, and polyetherimide-containing composition | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2025-08-19 | — | — | US | disclosed |
| US-20240317706-A1 | COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND METHODS OF USE THEREOF | MONTE ROSA THERAPEUTICS AG (CH) | 2024-09-26 | — | — | US | disclosed |
| EP-3394068-B1 | TDO2 INHIBITORS | GENENTECH INC (US) | 2024-09-11 | — | — | EP | disclosed |
| CN-117858865-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |
| CN-113166151-B | Substituted xanthine derivatives | 勃林格殷格翰国际有限公司 | 2023-12-01 | — | — | CN | disclosed |
| EP-3894410-B1 | SUBSTITUTED XANTHINE DERIVATIVES | BOEHRINGER INGELHEIM INT (DE) | 2023-10-11 | — | — | EP | disclosed |
| WO-2023069720-A1 | COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND METHODS OF USE THEREOF | MONTE ROSA THERAPEUTICS, INC. (US) | 2023-04-27 | — | — | WO | disclosed |
| CN-113748155-B | Methods of forming semi-crystalline polyetherimides and compositions comprising polyetherimides | 高新特殊工程塑料全球技术有限公司 | 2022-07-22 | — | — | CN | disclosed |
| US-20220177479-A1 | NOVEL SUBSTITUTED XANTHINE DERIVATIVES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2022-06-09 | — | — | US | disclosed |
| EP-3894410-A1 | SUBSTITUTED XANTHINE DERIVATIVES | Boehringer Ingelheim International GmbH (DE) | 2021-10-20 | — | — | EP | disclosed |
| CN-113166151-A | Substituted xanthine derivatives | 勃林格殷格翰国际有限公司 | 2021-07-23 | — | — | CN | disclosed |
| WO-2020234683-A1 | METHOD OF FORMING SEMICRYSTALLINE POLYETHERIMIDE, AND POLYETHERIMIDE-CONTAINING COMPOSITION | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2020-11-26 | — | — | WO | disclosed |
| EP-3741792-A1 | METHOD OF FORMING SEMICRYSTALLINE POLYETHERIMIDE, AND POLYETHERIMIDE-CONTAINING COMPOSITION | SABIC Global Technologies B.V. (NL) | 2020-11-25 | — | — | EP | disclosed |
| WO-2020120450-A1 | SUBSTITUTED XANTHINE DERIVATIVES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2020-06-18 | — | — | WO | disclosed |
| US-20200190093-A1 | SUBSTITUTED XANTHINE DERIVATIVES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2020-06-18 | — | — | US | disclosed |
| EP-3394068-A1 | TDO2 INHIBITORS | Genentech, Inc. (US) | 2018-10-31 | — | — | EP | disclosed |
| WO-2017107979-A1 | TDO2 INHIBITORS | GENENTECH, INC. (US) | 2017-06-29 | — | — | WO | disclosed |
| US-20090286958-A1 | INTERFERON-BETA FUSION PROTEINS AND USES | BIOGEN IDEC MA INC. (US) | 2009-11-19 | — | — | US | disclosed |