Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.66 |
| ▸ | NPC1 | O15118 | 7/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.66 |
| ▸ | PKM | P14618 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | POLB | P06746 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | ALPI | P09923 | 2/20 | 0.55 |
| ▸ | ALPG | P10696 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
| ▸ | AHR | P35869 | 1/20 | 0.55 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2299099 | 1.00 | RAB9A (0.66) | RAB9ANPC1SMN1; SMN2PKMKMT2A | |
| SCHEMBL8291968 | 0.79 | KMT2A (1.00) | RAB9ANPC1SMN1; SMN2PKMKMT2A | |
| SCHEMBL11887827 | 0.77 | RAB9A (0.81) | RAB9ANPC1SMN1; SMN2PKMKMT2A | |
| SCHEMBL2296888 | 0.76 | RAB9A (1.00) | RAB9ANPC1SMN1; SMN2PKMKMT2A | |
| SCHEMBL2296897 | 0.76 | RAB9A (1.00) | RAB9ANPC1SMN1; SMN2PKMKMT2A | |
| SCHEMBL8292186 | 0.74 | CYP1A2 (0.71) | PKMKMT2AALDH1A1CYP1A2MAPT | |
| SCHEMBL30808832 | 0.72 | NPC1 (0.62) | RAB9ANPC1SMN1; SMN2PKMKMT2A | |
| SCHEMBL1562660 | 0.72 | CYP1A2 (0.76) | RAB9ANPC1PKMKMT2AALDH1A1 | |
| SCHEMBL6635372 | 0.72 | CYP1A2 (0.76) | RAB9ANPC1PKMKMT2AALDH1A1 | |
| SCHEMBL1562661 | 0.72 | CYP1A2 (0.76) | RAB9ANPC1PKMKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011085351-A2 | METHOD OF TREATING KCNQ RELATED DISORDERS | THE JOHNS HOPKINS UNIVERSITY (US) | 2011-07-14 | — | — | WO | claimed |
| EP-4584250-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS | Biohaven Therapeutics Ltd. (VG) | 2025-07-16 | — | — | EP | disclosed |
| EP-4580679-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS AND NMDA RECEPTOR ANTAGONISTS | Biohaven Therapeutics Ltd. (VG) | 2025-07-09 | — | — | EP | disclosed |
| WO-2024054807-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS AND TDP-43 MODULATORS | BIOHAVEN THERAPEUTICS LTD. (VG) | 2024-03-14 | — | — | WO | disclosed |
| WO-2024054811-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS | BIOHAVEN THERAPEUTICS LTD. (VG) | 2024-03-14 | — | — | WO | disclosed |
| WO-2024050389-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS AND NMDA RECEPTOR ANTAGONISTS | BIOHAVEN THERAPEUTICS LTD. (VG) | 2024-03-07 | — | — | WO | disclosed |
| WO-2011085351-A2 | METHOD OF TREATING KCNQ RELATED DISORDERS | THE JOHNS HOPKINS UNIVERSITY (US) | 2011-07-14 | — | — | WO | disclosed |