Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13408055 | 0.89 | TSHR (0.51) | TSHRALOX15L3MBTL1MAPK1SCN5A | |
| SCHEMBL12414979 | 0.87 | TSHR (0.48) | TSHRALOX15L3MBTL1SCN5ASCN9A | |
| SCHEMBL18613163 | 0.82 | TSHR (0.47) | TSHRALOX15L3MBTL1SCN5ASCN9A | |
| SCHEMBL10228449 | 0.82 | TSHR (0.47) | TSHRALOX15L3MBTL1SCN5ASCN9A | |
| SCHEMBL19880291 | 0.81 | ALOX15 (0.43) | TSHRALOX15L3MBTL1SCN5ASCN9A | |
| SCHEMBL9945946 | 0.79 | MAPK1 (0.49) | TSHRALOX15MAPK1SCN5ASCN9A | |
| SCHEMBL13408054 | 0.78 | TSHR (0.47) | TSHRALOX15SCN5ASCN9ASCN10A | |
| SCHEMBL10299386 | 0.78 | TSHR (0.49) | TSHRALOX15L3MBTL1SCN5ASCN9A | |
| SCHEMBL13408056 | 0.77 | L3MBTL1 (0.46) | TSHRALOX15L3MBTL1MAPK1SCN5A | |
| SCHEMBL13901957 | 0.77 | TSHR (0.46) | TSHRALOX15L3MBTL1SCN5ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210047457-A1 | COMPOUND, RESIN, COMPOSITION AND PATTERN FORMATION METHOD | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2021-02-18 | — | — | US | disclosed |