Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25504696 | 0.80 | POLB (0.46) | ABL1RIN1POLB | |
| SCHEMBL6466613 | 0.80 | POLB (0.52) | ABL1RIN1POLB | |
| SCHEMBL21886710 | 0.80 | POLB (0.52) | ABL1RIN1POLB | |
| SCHEMBL25512274 | 0.80 | POLB (0.42) | ABL1RIN1POLBP2RX3TMIGD3 | |
| SCHEMBL5953531 | 0.80 | POLB (0.52) | ABL1RIN1POLB | |
| SCHEMBL26455112 | 0.79 | ABL1 (0.40) | ABL1RIN1POLBCYP2C9ADORA3 | |
| SCHEMBL26455083 | 0.79 | ABL1 (0.42) | ABL1RIN1POLBCYP2C9ADORA3 | |
| SCHEMBL25504697 | 0.78 | POLB (0.46) | ABL1RIN1POLBCYP2C9MAPT | |
| SCHEMBL769771 | 0.78 | ABL1 (0.38) | ABL1RIN1POLBCYP2C9ADORA3 | |
| SCHEMBL769394 | 0.76 | ABL1 (0.38) | ABL1RIN1POLBCYP2C9ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021030763-A1 | MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF | IONIS PHARMACEUTICALS, INC. (US) | 2021-02-18 | — | — | WO | disclosed |