Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | CDC25B | P30305 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | CASP1 | P29466 | 3/20 | 0.34 |
| ▸ | BLM | P54132 | 3/20 | 0.34 |
| ▸ | CASP7 | P55210 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1665290 | 0.82 | MAOA (0.43) | MAOAMAOBCDC25BSMN1; SMN2TP53 | |
| SCHEMBL6805580 | 0.69 | CDC25B (0.39) | CDC25B | |
| SCHEMBL94097 | 0.69 | MEN1 (0.41) | MAOAMAOBCDC25BSMN1; SMN2MAPT | |
| SCHEMBL7232074 | 0.67 | MAOA (0.52) | MAOAMAOBCDC25BSMN1; SMN2TP53 | |
| SCHEMBL31289313 | 0.66 | MAOA (0.34) | MAOAMAOBCDC25B | |
| SCHEMBL30956639 | 0.65 | MAOA (0.70) | MAOAMAOBCDC25BSMN1; SMN2TP53 | |
| SCHEMBL8417659 | 0.65 | MAOA (0.86) | MAOAMAOBCDC25BSMN1; SMN2TP53 | |
| SCHEMBL20618218 | 0.65 | MAOA (0.77) | MAOAMAOBCDC25BSMN1; SMN2TP53 | |
| SCHEMBL31112247 | 0.65 | MAOA (0.77) | MAOAMAOBCDC25BSMN1; SMN2TP53 | |
| SCHEMBL30616365 | 0.65 | MAOA (0.86) | MAOAMAOBCDC25BSMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2536721-A1 | PYRAZOLO PIPERIDINE DERIVATIVES AS NADPH OXIDASE INHIBITORS | GenKyoTex SA (CH) | 2012-12-26 | — | — | EP | claimed |
| WO-2011101805-A1 | PYRAZOLO PIPERIDINE DERIVATIVES AS NADPH OXIDASE INHIBITORS | GENKYOTEX SA (CH) | 2011-08-25 | — | — | WO | claimed |
| WO-2011101805-A1 | PYRAZOLO PIPERIDINE DERIVATIVES AS NADPH OXIDASE INHIBITORS | GENKYOTEX SA (CH) | 2011-08-25 | — | — | WO | disclosed |
| EP-0781816-B1 | Dyes for use in diverse applications | AGFA GEVAERT NV (BE) | 1999-06-16 | — | — | EP | disclosed |
| EP-0781816-A1 | New dyes for use in diverse applications | AGFA-GEVAERT N.V. (BE) | 1997-07-02 | — | — | EP | disclosed |