SCHEMBL20618218

SCHEMBL20618218

O=C1c2cnccc2-c2ccncc21

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAOA P21397 1/20 0.77
▸ MAOB P27338 1/20 0.77
▸ CDC25B P30305 2/20 0.67
▸ SMN1; SMN2 Q16637 5/20 0.52
▸ MAPT P10636 4/20 0.52
▸ BLM P54132 4/20 0.52
▸ CYP3A4 P08684 4/20 0.52
▸ TP53 P04637 3/20 0.52
▸ CASP1 P29466 3/20 0.52
▸ CASP7 P55210 2/20 0.52
▸ TSHR P16473 2/20 0.52
▸ MAPK1 P28482 1/20 0.52
▸ KDM4E B2RXH2 3/20 0.50
▸ RPS6KA3 P51812 1/20 0.43
▸ FGFR1 P11362 1/20 0.41
▸ SRC P12931 1/20 0.41
▸ FGFR2 P21802 1/20 0.41
▸ FGFR4 P22455 1/20 0.41
▸ FGFR3 P22607 1/20 0.41
▸ NPSR1 Q6W5P4 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31112247 1.00 MAOA (0.77) MAOAMAOBCDC25BSMN1; SMN2MAPT
SCHEMBL30616365 0.94 MAOA (0.86) MAOAMAOBCDC25BSMN1; SMN2MAPT
SCHEMBL8417659 0.94 MAOA (0.86) MAOAMAOBCDC25BSMN1; SMN2MAPT
SCHEMBL16685145 0.94 MAOA (0.70) MAOAMAOBCDC25BSMN1; SMN2MAPT
SCHEMBL6926901 0.91 MAOA (0.95) MAOAMAOBCDC25BSMN1; SMN2MAPT
SCHEMBL9269089 0.89 MAOA (0.77) MAOAMAOBCDC25BSMN1; SMN2MAPT
SCHEMBL29350676 0.87 MAOA (1.00) MAOAMAOBCDC25BSMN1; SMN2MAPT
SCHEMBL421291 0.87 MAOA (1.00) MAOAMAOBCDC25BSMN1; SMN2MAPT
SCHEMBL19013209 0.85 MAOA (0.87) MAOAMAOBCDC25BSMN1; SMN2MAPT
SCHEMBL3066734 0.85 MAOA (0.87) MAOAMAOBCDC25BSMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11661546-B2 Electrochromic element, optical filter, lens unit, image pickup apparatus, and window member CANON KABUSHIKI KAISHA (JP) 2023-05-30 — — US disclosed
US-11661546-B2 Electrochromic element, optical filter, lens unit, image pickup apparatus, and window member CANON KABUSHIKI KAISHA (JP) 2023-05-30 — — US disclosed
US-20210294008-A1 LIGHT-CONTROLLING DEVICE CANON KABUSHIKI KAISHA (JP) 2021-09-23 — — US disclosed
EP-3696602-A1 ELECTROCHROMIC ELEMENT, OPTICAL FILTER, LENS UNIT, IMAGING DEVICE, AND WINDOW MATERIAL C/o Canon Kabushiki Kaisha (JP) 2020-08-19 — — EP disclosed
US-20200241377-A1 ELECTROCHROMIC ELEMENT, OPTICAL FILTER, LENS UNIT, IMAGE PICKUP APPARATUS, AND WINDOW MEMBER CANON KABUSHIKI KAISHA (JP) 2020-07-30 — — US disclosed
US-20200233277-A1 ELECTROCHROMIC ELEMENT, OPTICAL FILTER, LENS UNIT, IMAGE PICKUP APPARATUS, AND WINDOW MEMBER CANON KABUSHIKI KAISHA (JP) 2020-07-23 — — US disclosed
US-20190353971-A1 ELECTROCHROMIC ELEMENT, IMAGING APPARATUS AND TRANSMITTANCE VARIABLE WINDOW USING THE SAME CANON KABUSHIKI KAISHA (JP) 2019-11-21 — — US disclosed
US-20190002758-A1 ORGANIC COMPOUND, ELECTROCHROMIC DEVICE, ELECTROCHROMIC APPARATUS, OPTICAL FILTER, IMAGE PICKUP APPARATUS, LENS UNIT, AND WINDOW MEMBER CANON KABUSHIKI KAISHA (JP) 2019-01-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190002758-A1 ORGANIC COMPOUND, ELECTROCHROMIC DEVICE, ELECTROCHROMIC APPARATUS, OPTICAL FILTER, IMAGE PICKUP APPARATUS, LENS UNIT, AND WINDOW MEMBER HCN2, EML4, KCNJ6 MAOA 1362/4885MAOB 1532/4885CDC25B 1478/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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