SCHEMBL22993129

SCHEMBL22993129

FC(F)(F)Oc1ccc(-c2cc(-c3cc4ccccc4c4ccccc34)c3cc4cc(-c5cccc(C(F)(F)F)c5)ccc4c(-c4cc5ccccc5c5ccccc45)c3c2)cc1

nearest known ligand 0.36

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 3/20 0.34
CYP11B2 P19099 3/20 0.34
SERPINE1 P05121 1/20 0.34
KDM4E B2RXH2 1/20 0.34
MAPT P10636 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
CYP1A1 P04798 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP1B1 Q16678 1/20 0.33
DHFR P00374 2/20 0.33
PLAU P00749 2/20 0.32
PLAT P00750 2/20 0.32
PLG P00747 1/20 0.32
PGR P06401 1/20 0.32
ABL1 P00519 1/20 0.32
NR1H4 Q96RI1 1/20 0.32
ACP1 P24666 1/20 0.32
ABCG2 Q9UNQ0 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22993379 1.00 CYP11B1 (0.34) CYP11B1CYP11B2SERPINE1KDM4EMAPT
SCHEMBL22993528 0.93 CYP11B1 (0.34) CYP11B1CYP11B2SERPINE1DHFRACP1
SCHEMBL22993079 0.93 CYP11B1 (0.34) CYP11B1CYP11B2SERPINE1DHFRACP1
SCHEMBL22993143 0.92 CYP11B1 (0.36) CYP11B1CYP11B2SERPINE1ACP1
SCHEMBL26211952 0.91 SERPINE1 (0.38) CYP11B1CYP11B2SERPINE1KDM4EMAPT
SCHEMBL22993123 0.91 CYP1A1 (0.38) CYP11B1CYP11B2KDM4ECYP1A1CYP1A2
SCHEMBL22993081 0.90 EPHX2 (0.38) CYP11B1CYP11B2KDM4ECYP1A1CYP1A2
SCHEMBL22993526 0.90 EPHX2 (0.38) CYP11B1CYP11B2KDM4ECYP1A1CYP1A2
SCHEMBL22993049 0.89 SERPINE1 (0.37) CYP11B1CYP11B2SERPINE1KDM4EMAPT
SCHEMBL22993365 0.88 PGR (0.40) CYP11B1CYP11B2KDM4ECYP1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230363196-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2023-11-09 US disclosed
US-20230363196-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2023-11-09 US disclosed
US-11751415-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2023-09-05 US disclosed
US-11751415-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2023-09-05 US disclosed
US-20210047536-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS, INC. (CA) 2021-02-18 US disclosed