SCHEMBL22993143

SCHEMBL22993143

FC(F)(F)Oc1ccc(-c2ccc3c(-c4cc5ccccc5c5ccccc45)c4cc(-c5ccc(OC(F)(F)F)cc5)cc(-c5cc6ccccc6c6ccccc56)c4cc3c2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 3/20 0.36
CYP11B2 P19099 3/20 0.36
ACP1 P24666 1/20 0.36
KIF11 P52732 1/20 0.35
AURKA O14965 1/20 0.35
TPX2 Q9ULW0 1/20 0.35
SCN5A Q14524 1/20 0.34
SERPINE1 P05121 2/20 0.33
JAK2 O60674 1/20 0.33
PRKD3 O94806 1/20 0.33
MARK3 P27448 1/20 0.33
PRKCI P41743 1/20 0.33
PRKCD Q05655 1/20 0.33
CAMK2B Q13554 1/20 0.33
CAMK2G Q13555 1/20 0.33
CAMK2D Q13557 1/20 0.33
BRSK1 Q8TDC3 1/20 0.33
PIM2 Q9P1W9 1/20 0.33
MAP4K5 Q9Y4K4 1/20 0.33
MMP3 P08254 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22993525 0.96 GPR84 (0.35) CYP11B1CYP11B2ACP1KIF11AURKA
SCHEMBL22992953 0.96 GPR84 (0.35) CYP11B1CYP11B2ACP1KIF11AURKA
SCHEMBL22993528 0.95 CYP11B1 (0.34) CYP11B1CYP11B2ACP1KIF11AURKA
SCHEMBL22993496 0.95 ACP1 (0.35) CYP11B1CYP11B2ACP1KIF11AURKA
SCHEMBL22993530 0.95 ACP1 (0.35) CYP11B1CYP11B2ACP1KIF11AURKA
SCHEMBL22993079 0.95 CYP11B1 (0.34) CYP11B1CYP11B2ACP1KIF11AURKA
SCHEMBL26803588 0.94 KIF11 (0.34) CYP11B1CYP11B2ACP1KIF11AURKA
SCHEMBL22993125 0.94 KIF11 (0.34) CYP11B1CYP11B2ACP1KIF11AURKA
SCHEMBL22993138 0.93 GPR84 (0.39) CYP11B1CYP11B2ACP1KIF11AURKA
SCHEMBL22993494 0.93 GPR84 (0.39) CYP11B1CYP11B2ACP1KIF11AURKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230363196-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2023-11-09 US disclosed
US-20230363196-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2023-11-09 US disclosed
US-11751415-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2023-09-05 US disclosed
US-11751415-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2023-09-05 US disclosed
US-20210047536-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS, INC. (CA) 2021-02-18 US disclosed