SCHEMBL22993142

SCHEMBL22993142

Cc1ccc(-c2ccc3c(-c4cc5ccccc5c5ccccc45)c4cc(-c5ccc(C(F)(F)F)cc5)cc(-c5cc6ccccc6c6ccccc56)c4cc3c2)cc1

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 2/20 0.37
P2RY14 Q15391 5/20 0.35
SLC6A2 P23975 1/20 0.35
KIF11 P52732 1/20 0.33
ENPP1 P22413 1/20 0.33
TRPV1 Q8NER1 1/20 0.33
PTPN5 P54829 1/20 0.32
CHRM5 P08912 1/20 0.32
HTR1B P28222 1/20 0.32
CYP3A4 P08684 1/20 0.32
KCNH2 Q12809 1/20 0.32
PDK2 Q15119 1/20 0.32
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22992948 1.00 GPR84 (0.37) GPR84P2RY14SLC6A2KIF11ENPP1
SCHEMBL22993495 0.94 P2RY14 (0.38) GPR84P2RY14SLC6A2KIF11CHRM5
SCHEMBL22993080 0.93 PTPN5 (0.40) GPR84KIF11ENPP1PTPN5CYP3A4
SCHEMBL26803571 0.93 PTPN5 (0.40) GPR84KIF11ENPP1PTPN5CYP3A4
SCHEMBL22993536 0.91 GPR84 (0.42) GPR84P2RY14SLC6A2KIF11TRPV1
SCHEMBL22993367 0.90 GPR84 (0.37) GPR84P2RY14SLC6A2KIF11ENPP1
SCHEMBL22993134 0.90 GPR84 (0.37) GPR84P2RY14SLC6A2KIF11ENPP1
SCHEMBL22993341 0.90 KIF11 (0.39) GPR84P2RY14SLC6A2KIF11ENPP1
SCHEMBL22993081 0.89 EPHX2 (0.38) P2RY14SLC6A2KIF11
SCHEMBL22993526 0.89 EPHX2 (0.38) P2RY14SLC6A2KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230363196-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2023-11-09 US disclosed
US-20230363196-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2023-11-09 US disclosed
US-11751415-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2023-09-05 US disclosed
US-11751415-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2023-09-05 US disclosed
US-20210047536-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS, INC. (CA) 2021-02-18 US disclosed