SCHEMBL22993148

SCHEMBL22993148

CC(C)(C)c1ccc(-c2c3ccccc3c(-c3cc4ccccc4c4ccccc34)c3ccc(-c4ccc(C(F)(F)F)cc4)cc23)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.43
KIF11 P52732 5/20 0.37
TRPV1 Q8NER1 1/20 0.35
ESR1 P03372 2/20 0.34
CYP11B1 P15538 1/20 0.33
CYP11B2 P19099 1/20 0.33
SLC6A2 P23975 1/20 0.33
P2RY14 Q15391 1/20 0.33
CCNE2 O96020 1/20 0.32
CDK4 P11802 1/20 0.32
CCND1 P24385 1/20 0.32
CCNE1 P24864 1/20 0.32
CDK2 P24941 1/20 0.32
CYP1A1 P04798 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2E1 P05181 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C8 P10632 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2A6 P11509 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22993247 1.00 GPR84 (0.43) GPR84KIF11TRPV1ESR1CYP11B1
SCHEMBL22993349 0.97 GPR84 (0.44) GPR84KIF11TRPV1CYP11B1CYP11B2
SCHEMBL22993024 0.94 KIF11 (0.42) GPR84KIF11ESR1CYP11B1CYP11B2
SCHEMBL26217141 0.94 GPR84 (0.47) GPR84KIF11ESR1CYP11B1SLC6A2
SCHEMBL21235643 0.93 GPR84 (0.43) GPR84KIF11ESR1CYP11B1CCNE2
SCHEMBL22993013 0.92 GPR84 (0.41) GPR84KIF11ESR1CYP11B1CYP11B2
SCHEMBL22993002 0.91 KIF11 (0.44) GPR84KIF11CYP11B1CYP11B2SLC6A2
SCHEMBL26214203 0.91 GPR84 (0.49) GPR84KIF11CYP11B1SLC6A2CYP2D6
SCHEMBL22992969 0.91 KIF11 (0.44) GPR84KIF11CYP11B1CYP11B2SLC6A2
SCHEMBL22993041 0.91 GPR84 (0.40) GPR84KIF11ESR1CYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230363196-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2023-11-09 US disclosed
US-20230363196-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2023-11-09 US disclosed
US-11751415-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2023-09-05 US disclosed
US-11751415-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2023-09-05 US disclosed
US-20210047536-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS, INC. (CA) 2021-02-18 US disclosed