SCHEMBL22993155

SCHEMBL22993155

FC(F)(F)Oc1ccc(-c2cccc3c(-c4cccc5ccccc45)c4ccccc4cc23)cc1

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PPARG P37231 11/20 0.49
PPARA Q07869 11/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2C19 P33261 1/20 0.49
PPARD Q03181 1/20 0.49
ACP1 P24666 1/20 0.40
CHRNB4 P30926 1/20 0.39
CHRNA3 P32297 1/20 0.39
CHRNA7 P36544 1/20 0.39
PRKDC P78527 1/20 0.39
SERPINE1 P05121 1/20 0.38
TRPV1 Q8NER1 1/20 0.38
CYP11B1 P15538 1/20 0.38
CYP11B2 P19099 1/20 0.38
KIF11 P52732 1/20 0.37
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA9 Q16790 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22992949 0.91 PPARG (0.42) PPARGPPARACYP2C9CYP2C19PPARD
SCHEMBL22992966 0.88 PPARG (0.42) PPARGPPARACYP2C9CYP2C19PPARD
SCHEMBL22978411 0.88 PPARG (0.48) PPARGPPARACYP2C9CYP2C19PPARD
SCHEMBL22993549 0.85 PPARG (0.44) PPARGPPARACYP2C9CYP2C19PPARD
SCHEMBL22993227 0.83 PPARG (0.42) PPARGPPARACYP2C9CYP2C19PPARD
SCHEMBL22993334 0.83 PPARG (0.42) PPARGPPARACYP2C9CYP2C19PPARD
SCHEMBL22992967 0.82 SCN5A (0.42) PPARGPPARACYP2C9CYP2C19PPARD
SCHEMBL22993157 0.82 PPARG (0.44) PPARGPPARACYP2C9CYP2C19PPARD
SCHEMBL24605287 0.81 ACP1 (0.39) PPARGPPARACYP2C9CYP2C19PPARD
SCHEMBL22993152 0.80 GPR84 (0.48) CYP2C19CA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230363196-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2023-11-09 US disclosed
US-20230363196-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2023-11-09 US disclosed
US-11751415-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2023-09-05 US disclosed
US-11751415-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2023-09-05 US disclosed
US-20210047536-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS, INC. (CA) 2021-02-18 US disclosed