SCHEMBL22993227

SCHEMBL22993227

Fc1cc2c(-c3ccc(OC(F)(F)F)cc3)c3ccccc3c(-c3cccc4ccccc34)c2cc1F

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PPARG P37231 5/20 0.42
PPARA Q07869 5/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
PPARD Q03181 1/20 0.42
ACP1 P24666 1/20 0.39
TRPV1 Q8NER1 1/20 0.37
GPR3 P46089 2/20 0.36
KIF11 P52732 1/20 0.36
PRKDC P78527 1/20 0.36
CYP11B1 P15538 4/20 0.36
CYP11B2 P19099 4/20 0.36
SERPINE1 P05121 1/20 0.35
ENPP1 P22413 1/20 0.35
SCN5A Q14524 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22978411 0.92 PPARG (0.48) PPARGPPARACYP2C9CYP2C19PPARD
SCHEMBL22993334 0.90 PPARG (0.42) PPARGPPARACYP2C9CYP2C19PPARD
SCHEMBL22993157 0.89 PPARG (0.44) PPARGPPARACYP2C9CYP2C19PPARD
SCHEMBL22993373 0.88 PPARG (0.39) PPARGPPARACYP2C9CYP2C19PPARD
SCHEMBL22993352 0.87 ACP1 (0.39) ACP1TRPV1GPR3KIF11CYP11B1
SCHEMBL22993549 0.87 PPARG (0.44) PPARGPPARACYP2C9CYP2C19PPARD
SCHEMBL22993135 0.86 PPARG (0.38) PPARGPPARACYP2C9CYP2C19PPARD
SCHEMBL22993550 0.85 PPARG (0.41) PPARGPPARACYP2C9CYP2C19PPARD
SCHEMBL26803631 0.84 PPARG (0.39) PPARGPPARACYP2C9CYP2C19PPARD
SCHEMBL22993155 0.83 PPARG (0.49) PPARGPPARACYP2C9CYP2C19PPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230363196-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2023-11-09 US disclosed
US-20230363196-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2023-11-09 US disclosed
US-11751415-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2023-09-05 US disclosed
US-11751415-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2023-09-05 US disclosed
US-20210047536-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS, INC. (CA) 2021-02-18 US disclosed