SCHEMBL22993352

SCHEMBL22993352

Fc1cc2c(-c3ccc(OC(F)(F)F)cc3)c3ccccc3c(-c3cc4ccccc4c4ccccc34)c2cc1F

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ACP1 P24666 1/20 0.39
CYP11B1 P15538 4/20 0.39
CYP11B2 P19099 4/20 0.39
KIF11 P52732 1/20 0.36
HPRT1 P00492 1/20 0.36
GPR3 P46089 2/20 0.35
ALOX5 P09917 1/20 0.34
ALOX5AP P20292 1/20 0.34
FEN1 P39748 1/20 0.34
AURKA O14965 1/20 0.33
TPX2 Q9ULW0 1/20 0.33
PTGDR2 Q9Y5Y4 1/20 0.33
TRPV1 Q8NER1 1/20 0.33
DHODH Q02127 1/20 0.33
SCN5A Q14524 1/20 0.33
CSNK2A2 P19784 1/20 0.32
CSNK2B P67870 1/20 0.32
CSNK2A1 P68400 1/20 0.32
CSNK2A3 Q8NEV1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22993048 0.88 CYP11B1 (0.37) ACP1CYP11B1CYP11B2KIF11GPR3
SCHEMBL22993227 0.87 PPARG (0.42) ACP1CYP11B1CYP11B2KIF11GPR3
SCHEMBL22993072 0.87 ACP1 (0.41) ACP1CYP11B1CYP11B2KIF11AURKA
SCHEMBL22992970 0.87 ACP1 (0.41) ACP1CYP11B1CYP11B2KIF11AURKA
SCHEMBL22993150 0.86 KIF11 (0.37) ACP1CYP11B1CYP11B2KIF11ALOX5AP
SCHEMBL22993280 0.85 CYP11B1 (0.38) ACP1CYP11B1CYP11B2KIF11GPR3
SCHEMBL22993350 0.84 KIF11 (0.38) ACP1CYP11B1CYP11B2KIF11HPRT1
SCHEMBL22993151 0.84 CYP11B1 (0.36) ACP1CYP11B1CYP11B2KIF11AURKA
SCHEMBL22993300 0.84 CYP11B1 (0.36) ACP1CYP11B1CYP11B2KIF11AURKA
SCHEMBL22993011 0.82 ACP1 (0.40) ACP1CYP11B1CYP11B2KIF11GPR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230363196-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2023-11-09 US disclosed
US-20230363196-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2023-11-09 US disclosed
US-11751415-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2023-09-05 US disclosed
US-11751415-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2023-09-05 US disclosed
US-20210047536-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS, INC. (CA) 2021-02-18 US disclosed