SCHEMBL22993304

SCHEMBL22993304

FC(F)(F)c1ccc(-c2ccc3c(-c4cccc5ccccc45)c4cc(-c5ccc(C(F)(F)F)cc5)ccc4c(-c4cccc5ccccc45)c3c2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 2/20 0.44
PSD A5PKW4 1/20 0.41
CA12 O43570 3/20 0.40
CA1 P00915 3/20 0.40
CA2 P00918 3/20 0.40
CA9 Q16790 3/20 0.40
P2RY14 Q15391 2/20 0.39
ENPP1 P22413 1/20 0.39
AGXT P21549 1/20 0.38
KCNQ3 O43525 1/20 0.38
KCNQ2 O43526 1/20 0.38
SLC6A2 P23975 1/20 0.38
SCN5A Q14524 1/20 0.38
SCN9A Q15858 1/20 0.38
EPHX2 P34913 1/20 0.37
CYP1A1 P04798 2/20 0.37
CYP1A2 P05177 2/20 0.37
CYP1B1 Q16678 2/20 0.37
CYP2E1 P05181 1/20 0.37
CYP3A4 P08684 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22993548 0.95 CYP1A1 (0.44) KIF11PSDCA12CA1CA2
SCHEMBL22993087 0.95 TOP1 (0.42) KIF11PSDCA12CA1CA2
SCHEMBL22993275 0.93 KCNQ3 (0.40) KIF11PSDCA12CA1CA2
SCHEMBL22993083 0.93 ENPP1 (0.42) KIF11PSDCA12CA1CA2
SCHEMBL22993255 0.93 CA12 (0.41) KIF11PSDCA12CA1CA2
SCHEMBL22993329 0.92 ENPP1 (0.42) KIF11PSDCA12CA1CA2
SCHEMBL22993330 0.92 ENPP1 (0.42) KIF11PSDCA12CA1CA2
SCHEMBL22993209 0.91 PSD (0.38) KIF11PSDCA12CA1CA2
SCHEMBL22993331 0.91 ENPP1 (0.43) KIF11PSDCA12CA1CA2
SCHEMBL22993301 0.90 CYP1A1 (0.47) KIF11PSDCA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230363196-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2023-11-09 US disclosed
US-20230363196-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2023-11-09 US disclosed
US-11751415-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2023-09-05 US disclosed
US-11751415-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2023-09-05 US disclosed
US-20210047536-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS, INC. (CA) 2021-02-18 US disclosed