SCHEMBL22993255

SCHEMBL22993255

Cc1cc2c(-c3cccc4ccccc34)c3ccc(-c4ccc(C(F)(F)F)cc4)cc3c(-c3cccc4ccccc34)c2cc1C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 4/20 0.41
CA1 P00915 4/20 0.41
CA2 P00918 4/20 0.41
CA9 Q16790 4/20 0.41
KIF11 P52732 3/20 0.39
TP53 P04637 1/20 0.38
MAPT P10636 1/20 0.38
TNKS O95271 1/20 0.38
TNKS2 Q9H2K2 1/20 0.38
PARP2 Q9UGN5 1/20 0.38
PSD A5PKW4 1/20 0.37
P2RY14 Q15391 2/20 0.36
KCNQ3 O43525 2/20 0.35
KCNQ2 O43526 2/20 0.35
DHFR P00374 1/20 0.35
BACE1 P56817 1/20 0.35
ENPP1 P22413 1/20 0.35
SCN5A Q14524 1/20 0.35
SCN9A Q15858 1/20 0.35
ADRB3 P13945 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22993304 0.93 KIF11 (0.44) CA12CA1CA2CA9KIF11
SCHEMBL22993083 0.92 ENPP1 (0.42) CA12CA1CA2CA9KIF11
SCHEMBL22993153 0.92 MAPT (0.39) CA12CA1CA2CA9KIF11
SCHEMBL22993259 0.91 CYP1A1 (0.43) CA12CA1CA2CA9PSD
SCHEMBL22993331 0.90 ENPP1 (0.43) CA12CA1CA2CA9KIF11
SCHEMBL22993275 0.90 KCNQ3 (0.40) CA12CA1CA2CA9KIF11
SCHEMBL22993087 0.88 TOP1 (0.42) CA12CA1CA2CA9KIF11
SCHEMBL26218736 0.88 CA12 (0.41) CA12CA1CA2CA9MAPT
SCHEMBL22993548 0.88 CYP1A1 (0.44) CA12CA1CA2CA9KIF11
SCHEMBL22993014 0.88 KCNQ3 (0.39) CA12CA1CA2CA9KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230363196-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2023-11-09 US disclosed
US-20230363196-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2023-11-09 US disclosed
US-11751415-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2023-09-05 US disclosed
US-11751415-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2023-09-05 US disclosed
US-20210047536-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS, INC. (CA) 2021-02-18 US disclosed