SCHEMBL22993301

SCHEMBL22993301

FC(F)(F)c1cccc(-c2ccc3c(-c4cccc5ccccc45)c4cc(-c5cccc(C(F)(F)F)c5)ccc4c(-c4cccc5ccccc45)c3c2)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP1B1 Q16678 1/20 0.47
PGR P06401 1/20 0.41
MAOB P27338 2/20 0.40
PDPK1 O15530 1/20 0.40
CNR2 P34972 1/20 0.40
MAPK14 Q16539 1/20 0.40
PSD A5PKW4 1/20 0.40
KDM1A O60341 1/20 0.40
RORC P51449 1/20 0.39
RORB Q92753 1/20 0.39
ADORA2A P29274 1/20 0.39
ADORA1 P30542 1/20 0.39
KDM4E B2RXH2 1/20 0.39
HPGD P15428 1/20 0.39
ATM Q13315 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22992996 0.97 CYP1A1 (0.45) CYP1A1CYP1A2CYP1B1PGRMAOB
SCHEMBL22993548 0.96 CYP1A1 (0.44) CYP1A1CYP1A2CYP1B1PGRMAOB
SCHEMBL22993532 0.94 PGR (0.43) CYP1A1CYP1A2CYP1B1PGRMAOB
SCHEMBL22993259 0.94 CYP1A1 (0.43) CYP1A1CYP1A2CYP1B1PGRMAOB
SCHEMBL22993085 0.92 PTPN5 (0.46) CYP1A1CYP1A2CYP1B1PGRMAOB
SCHEMBL22993302 0.91 CYP1A1 (0.41) CYP1A1CYP1A2CYP1B1PGRMAOB
SCHEMBL22993319 0.91 PGR (0.44) CYP1A1CYP1A2CYP1B1PGRMAOB
SCHEMBL22993318 0.91 ENPP1 (0.43) CYP1A1CYP1A2CYP1B1PGRPDPK1
SCHEMBL22993304 0.90 KIF11 (0.44) CYP1A1CYP1A2CYP1B1PSDCA12
SCHEMBL22978407 0.90 CYP1A1 (0.47) CYP1A1CYP1A2CYP1B1MAOBCNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230363196-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2023-11-09 US disclosed
US-20230363196-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2023-11-09 US disclosed
US-11751415-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2023-09-05 US disclosed
US-11751415-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2023-09-05 US disclosed
US-20210047536-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS, INC. (CA) 2021-02-18 US disclosed