Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22993030 | 0.86 | KDM4E (0.35) | KDM4E | |
| SCHEMBL22993268 | 0.80 | — | — | |
| SCHEMBL24253510 | 0.80 | HTR2A (0.33) | — | |
| SCHEMBL29388726 | 0.78 | MAOA (0.33) | — | |
| SCHEMBL25975831 | 0.77 | AVPR1A (0.31) | — | |
| SCHEMBL22993424 | 0.76 | PDK2 (0.33) | — | |
| SCHEMBL23416656 | 0.76 | — | — | |
| SCHEMBL22993439 | 0.73 | KDM4E (0.38) | KDM4E | |
| SCHEMBL23416680 | 0.71 | AVPR1A (0.33) | — | |
| SCHEMBL24253334 | 0.69 | KDM4E (0.34) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021028649-A1 | PLASMA KALLIKREIN INHIBITORS | KALVISTA PHARMACEUTICALS LIMITED (GB) | 2021-02-18 | — | — | WO | disclosed |
| WO-2021028645-A1 | PLASMA KALLIKREIN INHIBITORS | KALVISTA PHARMACEUTICALS LIMITED (GB) | 2021-02-18 | — | — | WO | disclosed |