Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22993489 | 0.81 | POLB (0.30) | POLB | |
| SCHEMBL24253302 | 0.79 | — | — | |
| SCHEMBL22993441 | 0.77 | — | — | |
| SCHEMBL22993433 | 0.72 | — | — | |
| SCHEMBL15983224 | 0.65 | GLS (0.31) | — | |
| SCHEMBL30755825 | 0.61 | — | — | |
| SCHEMBL12947559 | 0.61 | — | — | |
| SCHEMBL24253233 | 0.61 | CCNT1 (0.33) | — | |
| SCHEMBL22993428 | 0.60 | — | — | |
| SCHEMBL23847680 | 0.60 | DRD2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021028645-A1 | PLASMA KALLIKREIN INHIBITORS | KALVISTA PHARMACEUTICALS LIMITED (GB) | 2021-02-18 | — | — | WO | disclosed |
| WO-2021028649-A1 | PLASMA KALLIKREIN INHIBITORS | KALVISTA PHARMACEUTICALS LIMITED (GB) | 2021-02-18 | — | — | WO | disclosed |