⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6124223 | 0.81 | — | — | |
| SCHEMBL2629330 | 0.69 | — | — | |
| SCHEMBL9344670 | 0.67 | — | — | |
| SCHEMBL7847803 | 0.67 | — | — | |
| SCHEMBL25001383 | 0.67 | — | — | |
| SCHEMBL19447778 | 0.65 | ACHE (0.33) | — | |
| SCHEMBL12262831 | 0.64 | — | — | |
| SCHEMBL16848183 | 0.64 | GABRA1 (0.36) | — | |
| Formamide SCHEMBL27374035 | 0.63 | — | — | |
| SCHEMBL18539690 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021028645-A1 | PLASMA KALLIKREIN INHIBITORS | KALVISTA PHARMACEUTICALS LIMITED (GB) | 2021-02-18 | — | — | WO | disclosed |
| WO-2021028649-A1 | PLASMA KALLIKREIN INHIBITORS | KALVISTA PHARMACEUTICALS LIMITED (GB) | 2021-02-18 | — | — | WO | disclosed |