Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 2/20 | 0.32 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15121170 | 0.82 | ACHE (0.31) | ACHE | |
| SCHEMBL10207749 | 0.82 | GPR3 (0.40) | ACHE | |
| SCHEMBL17570170 | 0.82 | ACHE (0.33) | ACHE | |
| SCHEMBL21436805 | 0.79 | EPAS1 (0.33) | EPAS1SLC5A1 | |
| SCHEMBL14473474 | 0.77 | CETP (0.35) | — | |
| SCHEMBL24610706 | 0.75 | — | — | |
| SCHEMBL29706891 | 0.74 | MAOB (0.35) | EPAS1SLC5A1 | |
| SCHEMBL21437029 | 0.74 | MAOB (0.35) | EPAS1SLC5A1 | |
| SCHEMBL12329622 | 0.73 | PPARA (0.46) | — | |
| SCHEMBL10203675 | 0.72 | TP53 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021045159-A1 | THERAPEUTIC OR PROPHYLACTIC METHOD FOR DIABETES USING COMBINATION MEDICINE | 日本たばこ産業株式会社 | 2021-03-11 | — | — | WO | disclosed |
| EP-3778593-A1 | HETEROARYL-SUBSTITUTED PYRAZOLE COMPOUND AND MEDICINAL USE THEREOF | Japan Tobacco Inc. (JP) | 2021-02-17 | — | — | EP | disclosed |