Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 3/20 | 0.56 |
| ▸ | PPARG | P37231 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MMP1 | P03956 | 3/20 | 0.50 |
| ▸ | MMP2 | P08253 | 3/20 | 0.50 |
| ▸ | MMP9 | P14780 | 3/20 | 0.50 |
| ▸ | EGFR | P00533 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3161158 | 1.00 | NOS2 (0.56) | NOS2PPARGTDP1HDAC2HDAC3 | |
| SCHEMBL27337902 | 1.00 | NOS2 (0.56) | NOS2PPARGTDP1HDAC2HDAC3 | |
| SCHEMBL3161145 | 1.00 | NOS2 (0.56) | NOS2PPARGTDP1HDAC2HDAC3 | |
| SCHEMBL28229937 | 0.88 | AKR1B10 (0.51) | NOS2PPARGHDAC2HDAC3HDAC4 | |
| SCHEMBL3713724 | 0.88 | AKR1B10 (0.51) | NOS2PPARGHDAC2HDAC3HDAC4 | |
| SCHEMBL12231308 | 0.88 | HTT (0.55) | NOS2PPARGTDP1HDAC2HDAC3 | |
| SCHEMBL22994334 | 0.88 | HTT (0.55) | NOS2PPARGTDP1HDAC2HDAC3 | |
| SCHEMBL19717874 | 0.88 | AKR1B10 (0.51) | NOS2PPARGHDAC2HDAC3HDAC4 | |
| SCHEMBL3171423 | 0.88 | AKR1B10 (0.51) | NOS2PPARGHDAC2HDAC3HDAC4 | |
| SCHEMBL28230796 | 0.86 | NOS2 (0.73) | NOS2MMP1MMP2MMP9MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220304352-A1 | TASTE-MODIFYING COMPOUNDS AND USES THEREOF | FIRMENICH SA (CH) | 2022-09-29 | — | — | US | disclosed |
| WO-2021028106-A2 | TASTE-MODIFYING COMPOUNDS AND USES THEREOF | FIRMENICH SA (CH) | 2021-02-18 | — | — | WO | disclosed |