Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2295330 | 0.93 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2L3MBTL1PKMPOLB | |
| SCHEMBL2294711 | 0.91 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2L3MBTL1PKMPOLB | |
| SCHEMBL2294482 | 0.88 | NAMPT (0.48) | ALDH1A1SMN1; SMN2L3MBTL1MEN1KMT2A | |
| SCHEMBL2294002 | 0.86 | MEN1 (0.50) | ALDH1A1SMN1; SMN2L3MBTL1PKMPOLB | |
| SCHEMBL2295665 | 0.86 | PSEN1 (0.45) | ALDH1A1SMN1; SMN2L3MBTL1PKMMEN1 | |
| SCHEMBL2294905 | 0.85 | USP2 (0.51) | ALDH1A1SMN1; SMN2L3MBTL1POLBMEN1 | |
| SCHEMBL2299928 | 0.84 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2L3MBTL1PKMPOLB | |
| SCHEMBL2295180 | 0.84 | SMN1; SMN2 (0.47) | ALDH1A1SMN1; SMN2L3MBTL1PKMHTT | |
| SCHEMBL5291502 | 0.83 | BCHE (0.46) | SMN1; SMN2KMT2ANPC1RAB9ANAMPT | |
| SCHEMBL2298594 | 0.83 | KMT2A (0.46) | ALDH1A1PKMMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8003806-B2 | Integrin antagonists useful as anticancer agents | OSI Pharmaceuticals, LLC (US) | 2011-08-23 | — | — | US | claimed |
| US-20060116383-A1 | Integrin antagonists useful as anticancer agents | ALCATEL LUCENT (FR) | 2006-06-01 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060116383-A1 | Integrin antagonists useful as anticancer agents | ITGB5, ITGA5, ITGB1 | ALDH1A1 1381/4885SMN1; SMN2 2159/4885L3MBTL1 1292/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.