Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | DHODH | Q02127 | 13/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.31 |
| ▸ | ALPL | P05186 | 1/20 | 0.31 |
| ▸ | ALPI | P09923 | 1/20 | 0.31 |
| ▸ | ALPG | P10696 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8186780 | 0.84 | DHODH (0.33) | GAADHODHKDM4EALDH1A1 | |
| SCHEMBL8190377 | 0.81 | IGF1R (0.33) | — | |
| SCHEMBL8177653 | 0.81 | CYP4F2 (0.39) | KDM4EALDH1A1 | |
| SCHEMBL8177100 | 0.81 | GAA (0.33) | GAAKDM4EALPLALPIALPG | |
| SCHEMBL8185579 | 0.80 | KDM4E (0.36) | KDM4EALDH1A1 | |
| SCHEMBL8193219 | 0.75 | KDM4E (0.32) | GAAKDM4EALDH1A1ALPLALPI | |
| SCHEMBL22996403 | 0.72 | BRD4 (0.33) | GAAKDM4EALDH1A1 | |
| SCHEMBL960542 | 0.64 | KDM4E (0.39) | KDM4EALDH1A1 | |
| SCHEMBL8205156 | 0.62 | GAA (0.42) | GAAKDM4EALDH1A1ALPLALPI | |
| SCHEMBL5955774 | 0.61 | ALDH1A1 (0.74) | KDM4EALDH1A1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1021447-A1 | PYRROLOPYRAZOLOPYRIMIDINE COMPOUND AND MEDICINE COMPRISING THE SAME | POLA CHEMICAL INDUSTRIES, INC. (JP) | 2000-07-26 | — | — | EP | disclosed |
| WO-1998033799-A1 | PYRROLOPYRAZOLOPYRIMIDINE COMPOUND AND MEDICINE COMPRISING THE SAME | POLA CHEMICAL INDUSTRIES, INC. (JP) | 1998-08-06 | — | — | WO | disclosed |