Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22996401 | 1.00 | ALOX5 (0.35) | ALOX5MAOA | |
| SCHEMBL22996414 | 1.00 | ALOX5 (0.35) | ALOX5MAOA | |
| SCHEMBL23083768 | 0.78 | IRAK4 (0.36) | ALOX5MAOA | |
| SCHEMBL22996456 | 0.78 | IRAK4 (0.36) | ALOX5MAOA | |
| SCHEMBL23083774 | 0.78 | IRAK4 (0.36) | ALOX5MAOA | |
| SCHEMBL22560049 | 0.78 | — | — | |
| SCHEMBL22560050 | 0.74 | ALDH1A1 (0.31) | — | |
| SCHEMBL24879797 | 0.66 | LRRK2 (0.33) | ALOX5 | |
| SCHEMBL12409742 | 0.64 | — | — | |
| SCHEMBL10196436 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021027503-A1 | TRICYCLIC COMPOUND, PREPARATION METHOD THEREFOR, AND INTERMEDIATE AND USE THEREOF | 罗欣药业(上海)有限公司 | 2021-02-18 | — | — | WO | disclosed |