Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK7 | P50613 | 14/20 | 0.53 |
| ▸ | CCNH | P51946 | 14/20 | 0.53 |
| ▸ | MNAT1 | P51948 | 13/20 | 0.53 |
| ▸ | CCNE1 | P24864 | 11/20 | 0.53 |
| ▸ | CDK2 | P24941 | 11/20 | 0.53 |
| ▸ | CCNT1 | O60563 | 8/20 | 0.53 |
| ▸ | CDK9 | P50750 | 8/20 | 0.53 |
| ▸ | CDK1 | P06493 | 7/20 | 0.53 |
| ▸ | CDK4 | P11802 | 7/20 | 0.53 |
| ▸ | CCNB1 | P14635 | 7/20 | 0.53 |
| ▸ | CCND1 | P24385 | 7/20 | 0.53 |
| ▸ | CCND3 | P30281 | 7/20 | 0.53 |
| ▸ | CDK6 | Q00534 | 7/20 | 0.53 |
| ▸ | CCNK | O75909 | 8/20 | 0.40 |
| ▸ | CDK12 | Q9NYV4 | 8/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22997699 | 0.86 | CDK7 (0.41) | CDK7CCNHMNAT1CCNE1CDK2 | |
| SCHEMBL22977196 | 0.84 | CCNE1 (0.62) | CDK7CCNHMNAT1CCNE1CDK2 | |
| SCHEMBL22997821 | 0.84 | CDK7 (0.58) | CDK7CCNHMNAT1CCNE1CDK2 | |
| SCHEMBL22977124 | 0.82 | CCNE1 (0.75) | CDK7CCNHMNAT1CCNE1CDK2 | |
| SCHEMBL23001273 | 0.79 | CDK2 (0.46) | CDK7CCNHMNAT1CCNE1CDK2 | |
| SCHEMBL22997643 | 0.79 | CCNE1 (0.57) | CDK7CCNHMNAT1CCNE1CDK2 | |
| SCHEMBL22997763 | 0.78 | CCNE1 (0.48) | CDK7CCNHMNAT1CCNE1CDK2 | |
| SCHEMBL23001267 | 0.78 | CCNE1 (0.45) | CDK7CCNHMNAT1CCNE1CDK2 | |
| SCHEMBL22997803 | 0.77 | CCNE1 (0.42) | CDK7CCNHMNAT1CCNE1CDK2 | |
| SCHEMBL22997807 | 0.76 | CDK7 (0.51) | CDK7CCNHMNAT1CCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021030537-A1 | IMIDAZOLYL PYRIMIDINYLAMINE COMPOUNDS AS CDK2 INHIBITORS | INCYTE CORPORATION (US) | 2021-02-18 | — | — | WO | disclosed |
| US-20160340348-A1 | Cognition Enhancing Compounds and Compositions, Methods of Making, and Methods of Treating | MAPLIGHT THERAPEUTICS, INC. | 2016-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160340348-A1 | Cognition Enhancing Compounds and Compositions, Methods of Making, and Methods of Treating | CHRM3, CHRM4, CHRM5 | CDK7 835/4885CCNH 3943/4885MNAT1 1521/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.