SCHEMBL2300007

SCHEMBL2300007

CC(C)C[C@@H](C(=O)O)N(C)C(=O)OCc1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CTSK P43235 7/20 0.57
CTSB P07858 4/20 0.57
CTSS P25774 4/20 0.57
CTSL P07711 3/20 0.57
ABCB1 P08183 2/20 0.49
ITGB3 P05106 1/20 0.47
ITGA2B P08514 1/20 0.47
ALDH1A1 P00352 2/20 0.46
FOLH1 Q04609 1/20 0.44
MAPT P10636 1/20 0.43
HPGD P15428 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2497060 1.00 CTSK (0.57) CTSKCTSBCTSSCTSLABCB1
SCHEMBL7000046 1.00 CTSK (0.57) CTSKCTSBCTSSCTSLABCB1
Leucine SCHEMBL14693625 0.92 CTSK (0.52) CTSKCTSBCTSSCTSLABCB1
SCHEMBL16272898 0.91 CTSK (0.57) CTSKCTSBCTSSCTSLABCB1
Leucine SCHEMBL4294227 0.90 CTSK (0.50) CTSKCTSBCTSSCTSLABCB1
SCHEMBL26312471 0.90 CTSK (0.56) CTSKCTSBCTSSCTSLABCB1
SCHEMBL2302062 0.89 CTSK (0.49) CTSKCTSBCTSSCTSLABCB1
Leucine SCHEMBL2302063 0.89 CTSK (0.49) CTSKCTSBCTSSCTSLABCB1
SCHEMBL11306130 0.89 CTSK (0.58) CTSKCTSBCTSSCTSLABCB1
SCHEMBL11306127 0.89 CTSK (0.58) CTSKCTSBCTSSCTSLABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE30496-E Tripeptide derivatives with central nervous system activity and preparation thereof AYERST, MCKENNA & HARRISON, LTD. (CA) 1981-01-27 US claimed
US-4018912-A Tripeptide derivatives with central nervous system activity and preparation thereof AYERST MCKENNA AND HARRISON LTD. (CA) 1977-04-19 US claimed
EP-4733307-A1 METHOD FOR PRODUCING PEPTIDE COMPOUND USING MIXED ANHYDRIDE PROCEDURE CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2026-04-29 EP disclosed
EP-4612156-A1 ANTI-VIRAL COMPOUNDS Aligos Therapeutics, Inc. (US) 2025-09-10 EP disclosed
WO-2025070753-A1 METHOD FOR PRODUCING PEPTIDE COMPOUND USING MIXED ANHYDRIDE PROCEDURE 中外製薬株式会社 2025-04-03 WO disclosed
CN-118354782-A Compositions comprising peptide compounds for use in combination with surfactants 中外制药株式会社 2024-07-16 CN disclosed
US-20240199647-A1 ANTI-VIRAL COMPOUNDS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2024-06-20 US disclosed
CN-118176012-A Compositions comprising a peptide compound and a surfactant 中外制药株式会社 2024-06-11 CN disclosed
EP-4376834-A1 NOVEL SPIROPYRROLIDINE DERIVED ANTIVIRAL AGENTS Enanta Pharmaceuticals, Inc. (US) 2024-06-05 EP disclosed
CN-118043045-A Novel spiropyrrolidine derived antiviral drugs 英安塔制药有限公司 2024-05-14 CN disclosed
WO-2024097296-A1 ANTI-VIRAL COMPOUNDS ALIGOS THERAPEUTICS, INC. (US) 2024-05-10 WO disclosed
WO-1996013266-A1 BORONIC ESTER AND ACID COMPOUNDS, SYNTHESIS AND USES PROSCRIPT, INC. (US) 1996-05-09 WO disclosed
EP-0657173-A1 Endoparasiticide drugs on a basis of open chain hexadepsipeptides BAYER AG (DE) 1995-06-14 EP disclosed
EP-0644883-A1 ENNIATINES AND ENNIATINE DERIVATES USED TO CONTROL ENDOPARASITES BAYER AG (DE) 1995-03-29 EP disclosed
WO-1993025543-A2 ENNIATINES AND ENNIATINE DERIVATES USED TO CONTROL ENDOPARASITES BAYER AKTIENGESELLSCHAFT (DE) 1993-12-23 WO disclosed
EP-0520336-A2 Aldehyde derivatives and their use as calpain inhibitors FUJIREBIO Inc. (JP) 1992-12-30 EP disclosed
US-4250085-A PHOSPHONATE-CONTAINING OLIGOPEPTIDES, BACTERICIDES HOFFMANN-LA ROCHE INC. (US) 1981-02-10 US disclosed
US-RE30496-E Tripeptide derivatives with central nervous system activity and preparation thereof AYERST, MCKENNA & HARRISON, LTD. (CA) 1981-01-27 US disclosed
EP-0002822-A1 Phosphorus containing peptide derivatives, their production, intermediates for their production and pharmaceutical compositions containing them F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1979-07-11 EP disclosed
US-4018912-A Tripeptide derivatives with central nervous system activity and preparation thereof AYERST MCKENNA AND HARRISON LTD. (CA) 1977-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240199647-A1 ANTI-VIRAL COMPOUNDS EIF2AK2, ZC3HAV1, HAVCR2 CTSK 1688/4885CTSB 829/4885CTSS 649/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.