Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.50 |
| ▸ | CTSL | P07711 | 2/20 | 0.50 |
| ▸ | CTSB | P07858 | 2/20 | 0.50 |
| ▸ | CTSS | P25774 | 2/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.46 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.43 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.40 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Leucine SCHEMBL14693625 | 0.98 | CTSK (0.52) | CTSKCTSLCTSBCTSSSLC1A1 | |
| Leucine SCHEMBL2302063 | 0.94 | CTSK (0.49) | CTSKCTSLCTSBCTSSSLC1A1 | |
| SCHEMBL2300007 | 0.90 | CTSK (0.57) | CTSKCTSLCTSBCTSSABCB1 | |
| SCHEMBL7000046 | 0.90 | CTSK (0.57) | CTSKCTSLCTSBCTSSABCB1 | |
| SCHEMBL2497060 | 0.90 | CTSK (0.57) | CTSKCTSLCTSBCTSSABCB1 | |
| SCHEMBL2302062 | 0.85 | CTSK (0.49) | CTSKCTSLCTSBCTSSSLC1A1 | |
| SCHEMBL2299326 | 0.84 | CTSK (0.48) | CTSKCTSLCTSBCTSSSLC1A1 | |
| SCHEMBL16272898 | 0.82 | CTSK (0.57) | CTSKCTSLCTSBCTSSABCB1 | |
| SCHEMBL26312471 | 0.81 | CTSK (0.56) | CTSKCTSLCTSBCTSSABCB1 | |
| SCHEMBL11306127 | 0.80 | CTSK (0.58) | CTSKCTSLCTSBCTSSABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090247731-A1 | BORONIC ESTER AND ACID COMPOUNDS, SYNTHESIS AND USES | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2009-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247731-A1 | BORONIC ESTER AND ACID COMPOUNDS, SYNTHESIS AND USES | BCL6, BCAP31, CD79B | CTSK 2510/4885CTSL 3805/4885CTSB 461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.