Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 1/20 | 0.56 |
| ▸ | P2RY10 | O00398 | 4/20 | 0.53 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.49 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.49 |
| ▸ | LPAR4 | Q99677 | 2/20 | 0.49 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.49 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.49 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.49 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20472539 | 1.00 | FABP3 (0.56) | FABP3P2RY10GPR34ALDH1A1LPAR1 | |
| SCHEMBL9027639 | 1.00 | FABP3 (0.56) | FABP3P2RY10GPR34ALDH1A1LPAR1 | |
| SCHEMBL515226 | 1.00 | FABP3 (0.56) | FABP3P2RY10GPR34ALDH1A1LPAR1 | |
| SCHEMBL52780 | 1.00 | FABP3 (0.56) | FABP3P2RY10GPR34ALDH1A1LPAR1 | |
| SCHEMBL16180754 | 0.96 | FABP3 (0.53) | FABP3P2RY10GPR34ALDH1A1LPAR1 | |
| SCHEMBL5190825 | 0.92 | FABP3 (0.62) | FABP3P2RY10GPR34 | |
| SCHEMBL5475892 | 0.92 | FABP3 (0.62) | FABP3P2RY10GPR34 | |
| SCHEMBL1643923 | 0.92 | FABP3 (0.62) | FABP3P2RY10GPR34 | |
| SCHEMBL23166803 | 0.89 | ALDH1A1 (0.53) | FABP3ALDH1A1LPAR1ENPP2LPAR4 | |
| SCHEMBL23091273 | 0.89 | ALDH1A1 (0.53) | FABP3ALDH1A1LPAR1ENPP2LPAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3229811-B1 | PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS | GRI BIO INC (US) | 2021-02-24 | — | — | EP | disclosed |