SCHEMBL52780

SCHEMBL52780

CCCCCCCCC=CCCCCCCCCCCCC(=O)OP(=O)(O)OCC[N+](C)(C)C

nearest known ligand 0.57

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FABP3 P05413 1/20 0.56
P2RY10 O00398 4/20 0.53
GPR34 Q9UPC5 1/20 0.53
ALDH1A1 P00352 1/20 0.52
LPAR1 Q92633 5/20 0.49
ENPP2 Q13822 3/20 0.49
LPAR4 Q99677 2/20 0.49
LPAR5 Q9H1C0 2/20 0.49
LPAR2 Q9HBW0 2/20 0.49
LPAR3 Q9UBY5 2/20 0.49
CES2 O00748 1/20 0.49
LPAR6 P43657 1/20 0.49
TRPV1 Q8NER1 1/20 0.49
SLC6A5 Q9Y345 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23001085 1.00 FABP3 (0.56) FABP3P2RY10GPR34ALDH1A1LPAR1
SCHEMBL20472539 1.00 FABP3 (0.56) FABP3P2RY10GPR34ALDH1A1LPAR1
SCHEMBL9027639 1.00 FABP3 (0.56) FABP3P2RY10GPR34ALDH1A1LPAR1
SCHEMBL515226 1.00 FABP3 (0.56) FABP3P2RY10GPR34ALDH1A1LPAR1
SCHEMBL16180754 0.96 FABP3 (0.53) FABP3P2RY10GPR34ALDH1A1LPAR1
SCHEMBL5190825 0.92 FABP3 (0.62) FABP3P2RY10GPR34
SCHEMBL5475892 0.92 FABP3 (0.62) FABP3P2RY10GPR34
SCHEMBL1643923 0.92 FABP3 (0.62) FABP3P2RY10GPR34
SCHEMBL23166803 0.89 ALDH1A1 (0.53) FABP3ALDH1A1LPAR1ENPP2LPAR4
SCHEMBL23091273 0.89 ALDH1A1 (0.53) FABP3ALDH1A1LPAR1ENPP2LPAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 341 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4363043-B1 COMPOSITIONS FOR USE IN METHODS FOR INCREASING CANCER CELL SENSITIVITY TO ALTERNATING ELECTRIC FIELDS NOVOCURE GMBH (CH) 2026-04-22 EP claimed
US-12594421-B2 Compositions and methods for increasing cancer cell sensitivity to alternating electric fields NOVOCURE GMBH (CH) 2026-04-07 US claimed
US-20260053785-A1 COMBINATION THERAPY FOR TREATMENT OF CANCER PMV PHARMACEUTICALS INC (US) 2026-02-26 US claimed
US-20250339680-A1 COMPOSITIONS AND METHODS FOR INCREASING CANCER CELL SENSITIVITY TO ALTERNATING ELECTRIC FIELDS NOVOCURE GMBH (CH) 2025-11-06 US claimed
EP-4615431-A1 COMBINATION THERAPIES FOR THE TREATMENT OF CANCER Astrazeneca AB (SE) 2025-09-17 EP claimed
EP-4604957-A1 COMBINATIONS OF A SERD FOR THE TREATMENT OF CANCER Astrazeneca AB (SE) 2025-08-27 EP claimed
US-20250205233-A1 EPIDERMAL GROWTH FACTOR RECEPTOR (EGFR) TYROSINE KINASE INHIBITORS IN COMBINATION WITH AN AKT INHIBITOR FOR THE TREATMENT OF CANCER ASTRAZENECA AB (SE) 2025-06-26 US claimed
US-20250171518-A1 METHODS FOR PREPARING CELLS FOR ADOPTIVE T CELL THERAPY CITY OF HOPE 2025-05-29 US claimed
WO-2025083205-A1 DRUG COMBINATION COMPRISING ANTI-CD37 ANTIBODY MAYTANSINE CONJUGATE AND BCL2 INHIBITOR OR PI3K INHIBITOR DEBIOPHARM INTERNATIONAL S.A. (CH) 2025-04-24 WO claimed
EP-4519418-A1 METHODS FOR IMPROVING T CELL EFFICACY Immatics US, Inc. (US) 2025-03-12 EP claimed
WO-2007071658-A2 ALKYL PHOSPHOLIPID DERIVATIVES WITH REDUCED CYTOTOXICITY AND USES THEREOF ÆTERNA ZENTARIS GMBH (DE) 2007-06-28 WO claimed
EP-1800684-A1 Novel alkyl phospholipid derivatives and uses thereof Zentaris GmbH (DE) 2007-06-27 EP claimed
WO-2006121518-A2 ELECTRICAL DEVICES, ANTI-SCARRING AGENTS, AND THERAPEUTIC COMPOSITIONS ANGIOTECH INTERNATIONAL AG (CH) 2006-11-16 WO claimed
WO-2006121522-A2 IMPLANTABLE SENSORS AND PUMPS, ANTI-SCARRING AGENTS, AND THERAPEUTIC COMPOSITIONS ANGIOTECH INTERNATIONAL AG (CH) 2006-11-16 WO claimed
WO-2006118630-A2 PHOSPHOINOSITIDE MODULATION FOR THE TREATMENT OF ALZHEIMER'S DISEASE THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2006-11-09 WO claimed
US-20050165245-A1 Phospholipid-analogous compounds MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) 2005-07-28 US claimed
US-20030083313-A1 Treatment of breast cancer with a liposome mixture comprising an antineoplastic alkylphospholipid and water- or lipid-soluble antiestrogen agents MAX-DELBRUCK-CENTRUM FUR MOLEKULARE MEDIZIN (DE) 2003-05-01 US claimed
EP-1135193-B1 AGENTS PROVIDED FOR TREATING TUMORS, BASED ON LIPOSOMES, AND CONTAINING TAMOXIFEN MAX DELBRUECK CENTRUM (DE) 2002-10-30 EP claimed
EP-0507337-B1 Novel erucyl, brassidyl and nervonyl derivatives MAX PLANCK GESELLSCHAFT (DE) 1996-10-23 EP claimed
US-5436234-A Treatment of protozoal and fungal diseases, autoimmune diseases and bone marrow damage MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG (DE) 1995-07-25 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260053785-A1 COMBINATION THERAPY FOR TREATMENT OF CANCER TP53, PI4K2A, PIK3CA FABP3 4729/4885P2RY10 2306/4885GPR34 2386/4885
US-20250171518-A1 METHODS FOR PREPARING CELLS FOR ADOPTIVE T CELL THERAPY CD4, ICOS, CD2 FABP3 1079/4885P2RY10 4866/4885GPR34 3993/4885
US-12594421-B2 Compositions and methods for increasing cancer cell sensitivity to alternating electric fields PTK2, GSK3B, MTOR FABP3 3902/4885P2RY10 2300/4885GPR34 4212/4885
US-20250205233-A1 EPIDERMAL GROWTH FACTOR RECEPTOR (EGFR) TYROSINE KINASE INHIBITORS IN COMBINATION WITH AN AKT INHIBITOR FOR THE TREATMENT OF CANCER EGFR, ERBB2, ERBB3 FABP3 2973/4885P2RY10 4596/4885GPR34 2687/4885
US-20050165245-A1 Phospholipid-analogous compounds PHOSPHO1, SGMS1, SGMS2 FABP3 910/4885P2RY10 678/4885GPR34 2294/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.